He was elected as a Republican to the Thirty-fifth United States Congress to fill the vacancy caused by the death of Samuel Brenton; reelected to the Thirty-sixth United States Congress and served from December 7, 1857, to March 3, 1861; unsuccessful candidate for reelection in 1860 to the Thirty-seventh United States Congress.
Later career and death
During the Civil War, he served as first lieutenant and adjutant of the Forty-fourth Regiment, Indiana Volunteer Infantry; subsequently became a major in the Third Regiment, Indiana Volunteer Cavalry, and served from November 26, 1861, - August 15, 1862.
He later resumed the practice of his profession in Washington, D.C.
- United States Congress. "Charles Case (id: C000219)". Biographical Directory of the United States Congress.
- Peggy Seigel, "Charles Case: A Radical Republican in the Irrepressible Conflict," Indiana Magazine of History, vol. 107, no. 4 (Dec. 2011), pp. 327–360. In JSTOR