Mersalyl
Appearance
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Names | |
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IUPAC name
(3-{[2-(Carboxymethoxy)benzoyl]amino}-2-methoxypropyl)(hydroxy)mercury
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Other names
Mersalyl acid, salyrganic acid
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.943 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C13H18HgNO6 | |
Molar mass | 484.87512 g/mol |
Pharmacology | |
C03BC01 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Mersalyl (Mersal) is an organomercury compound[1] and mercurial diuretic. It is only rarely used as a drug, having been superseded by thiazides and loop diuretics that are less toxic because they do not contain mercury. It features a Hg(II) centre. Mersalyl was originally adapted from calomel (Hg2Cl2), a diuretic discovered by Paracelsus.
See also
- Thiomersal – Organomercury antiseptic and antifungal agent
- Nitromersol – Organomercury antiseptic and antifungal agent
References
- ^ Stewart, J. H.; Edwards, K. D. (1965). "Clinical comparison of frusemide with bendrofluazide, mersalyl, and ethacrynic acid". British Medical Journal. 2 (5473): 1277–1281. doi:10.1136/bmj.2.5473.1277. PMC 1846704. PMID 5849145.