ZC3H12A
Appearance
Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.[5]
ZC3H12A (also known as MCPIP-1 and Regnase-1) is an MCP1 (CCL2; MIM 158105)-induced protein that plays an important role in cell differentiation, apoptosis and the regulation of inflammation.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000163874 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042677 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Zinc finger CCCH-type containing 12A".
Further reading
- Liang J, Wang J, Azfer A, Song W, Tromp G, Kolattukudy PE, Fu M (2008). "A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages". The Journal of Biological Chemistry. 283 (10): 6337–46. doi:10.1074/jbc.M707861200. PMID 18178554.
- Jin Z, Zheng E, Sareli C, Kolattukudy PE, Niu J (2021). "Monocyte Chemotactic Protein-Induced Protein 1 (MCPIP-1): A Key Player of Host Defense and Immune Regulation". Front. Immunol. 12: 727861. doi:10.3389/fimmu.2021.727861. PMC 8519509. PMID 34659213.