User talk:Caredin161111

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Medisum is an Australian sponsor, that provides easy to use, naturally derived products that deliver holistic wellness through prevention and early intervention. ^[1]Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

Trim 1 + 1 is the very first product of the brand listed through TGA ^[2]. It contains natural active ingredients that are distributed in 2 formulations, which are Chitosan, Green tea extract, Chromium, Magnolia, Phaseolus vulgaris (white kidney bean), psyllium husk, Avena sativa, and Camellia sinensis, that may benefit the maintenance of a healthy body weight ^[3].Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

In the list of ingredients for the tablet formulation, chitosan has been discovered that in an acidic environment it acts as a soluble fiber, readily dispersing in the digestive secretions and food particles. Binding several times its weight in water, chitosan is thought to form a gel that traps and encapsulates dietary fats. As it passes in the small intestine, it encounters an environment that is no longer acidic. In a non-acidic environment, chitosan becomes insoluble and forms its gel-like complex with bound fats and bile acids leaving the fat indigestible with no caloric value. This insoluble complex passes undigested through the large intestine and is naturally eliminated. In addition, chitosan carries a positive charge, and the positive charge of chitosan attracts negatively charged fatty and bile acids. A decrease in bile activity would indirectly slow fat absorption. Depletion of excess body fat with minimal loss of fat or lean body mass under free-living conditions with proven safety has been demonstrated by this clinical study ^[4].Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

In addition, research has also shown green tea`s thermogenic properties owing to a synergistic interaction between caffeine and polyphenols. EGCG and caffeine modulate energy expenditure and substrate oxidation rates via different targets. EGCG can inhibit catechol O-methyltransferase (COMT), an enzyme involved in the degradation of norepinephrine. As a consequence, once released, norepinephrine remains in the synaptic cleft longer and provides a prolonged stimulation of adrenergic receptors. Caffeine also inhibits the phosphodiesterase-induced degradation of the intracellular cyclic AMP (cAMP). Both a prolonged stimulation of adrenergic receptors, specifically 𝛃-adrenergic receptors and an increased intracellular cAMP concentration result in an increase in energy expenditure and fat oxidation ^[5].Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

Meanwhile, chromium is stated as an essential trace element for humans and a component of Glucose Tolerance Factor that potentiates insulin`s activity and therefore regulates blood sugar levels ^[6]. Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

The use of Magnolia extracts is due to the recently established links between chronic stress and obesity. Honokiol and magnolol, extracted from Magnolia, have been proven by scientific clinical research to treat stress-related conditions involving elevated cortisol, such as control of body weight, sleep disturbances and restlessness ^[7]. Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

Among the ingredients utilized to formulate the sachet, White kidney bean has been examined in various clinical studies as an assisting substance for weight loss. This is mainly because it acts as amylase inhibitor that prevents starch from being digested and therefore absorbed. ^[8][9] Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

Moreover, Psyllium, a dietary fiber, functions to help lower blood sugar and cholesterol and mitigate the risk of heart disease and control obesity. Similarly, soluble and fermentable dietary fiber, beta-glucan from Avena sativa, also facilitates on the decrease of blood lipids ^[10][11].Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]

Last but not least, Cistanche deserticola is traditionally used to reduce constipation ^[12].Caredin161111 (talk) 23:31, 22 February 2018 (UTC)[reply]