User:Swouf/sandbox
Impact
3D bioprinting contributes to significant advances in the medical field of tissue engineering by allowing for research to be done on innovative materials called biomaterials. Biomaterials are the materials adapted and used for printing three-dimensional objects. Some of the most notable bioengineered substances are usually stronger than the average bodily materials, including soft tissue and bone. These constituents can act as future substitutes, even improvements, for the original body materials. Alginate, for example, is an anionic polymer with many biomedical implications including feasibility, strong biocompatibility, low toxicity, and stronger structural ability in comparison to some of the body's structural material.[1] Synthetic hydrogels are also commonplace, including PV-based gels. The combination of acid with a UV-initiated PV-based cross-linker has been evaluated by the Wake Forest Institute of Medicine and determined to be a suitable biomaterial.[2] Engineers are also exploring other options such as printing micro-channels that can maximize the diffusion of nutrients and oxygen from neighboring tissues[3] In addition, the Defense Threat Reduction Agency aims to print mini organs such as hearts, livers, and lungs as the potential to test new drugs more accurately and perhaps eliminate the need for testing in animals.[3]
- ^ Crawford, M. (May 2013). "Creating Valve Tissue Using 3-D Bioprinting". ASME.org. American Society of Mechanical Engineers. Retrieved 17 February 2016.
- ^ Murphy, S.V.; Skardal, A.; Atala, A. (2013). "Evaluation of hydrogels for bio-printing applications". Journal of Biomedical Materials Research Part A. 101A (1): 272–84. doi:10.1002/jbm.a.34326. PMID 22941807.
- ^ a b Cite error: The named reference
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