User:Mr. Ibrahem/Dextran 40
| Clinical data | |
|---|---|
| Trade names | LMD, Rheomacrodex, others |
| Other names | Low viscosity dextran[1] |
| AHFS/Drugs.com | Monograph |
| Drug class | Colloid[1] |
| Legal status | |
| Legal status |
|
| Chemical and physical data | |
| Molar mass | 70,000 Da |
Dextran 40, sold under the brand name LMD among others, is a type of fluid given by injection into a vein to expand blood volume.[2] Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available.[2] However, it does not carry oxygen.[3]
Side effects may include volume overload, kidney problems, acidosis, allergic reactionss, and poor blood clotting.[2] It is not recommended in severe kidney failure, heart failure, or clotting disorders.[2] Use may interfere with certain blood tests.[2]
Dextran 40 came into medical use in 1961.[4] It is a glucose polymer with a typical molecular weight of 40 kDa.[1][4] It works by pulling fluid from the extravascular space into the blood vessels.[2] It is a non protein based colloid solution.[2][1]
References
- ^ a b c d "DailyMed - LMD IN DEXTROSE- dextran 40 injection, solution LMD IN SODIUM CHLORIDE- dextran 40 injection, solution". dailymed.nlm.nih.gov. Archived from the original on 14 April 2021. Retrieved 23 December 2021.
- ^ a b c d e f g h i "Dextran 40 Monograph for Professionals". Drugs.com. Archived from the original on 3 January 2017. Retrieved 22 July 2021.
- ^ Howe, Tiffany; Burton, Angela (10 December 2019). Pharmacology for the Surgical Technologist - E-Book. Elsevier Health Sciences. p. 155. ISBN 978-0-323-66122-5. Archived from the original on 11 January 2022. Retrieved 23 December 2021.
- ^ a b Alexander, Martin; Bloom, Barry R.; Hopwood, David A.; Hull, Roger; Iglewski, Barbara H.; Laskin, Allen I.; Oliver, Stephen G.; Schaechter, Moselio; Summers, William C. (10 February 2000). Encyclopedia of Microbiology, Four-Volume Set. Academic Press. p. 562. ISBN 978-0-08-054848-7. Archived from the original on 11 January 2022. Retrieved 23 December 2021.