User:Maxwell.Bailey137/Economic epidemiology

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Economics, Epidemiology, and Pandemics: - DRAFT

The idea of intertwining epidemiology and economics is relatively new with it first appearing in the early 1990's amidst the HIV/AIDS epidemic. Epidemiologists at the time realized that the disease was spread through one's decisions around sex, and reasoned that it must then be considered an endogenous variable within the Nash-Equilibrium, therefor linking this with economics as the outcomes could then be predicted.[1] Both Economics and Epidemiology however have influence from Utilitarianism in the form of, "doing the most good for the most amount of people" or cost-benefit analysis as both fields of study hope to find net positives in the outcomes of their decisions.[2] However, the SARS-CoV-2 Pandemic and its fallout, has brought extremely relevant and timely data to researchers in this field. From January 1st, 2020 until December 4th, 2022 there has been a centrally estimated 1,277,204 excess deaths relating from the Covid-19 pandemic, with a majority of deaths consisting of the disease.[3] Somewhat similar to John Snow discovering the vector for cholera through water pumps, epidemiologists were able to track community spread of Covid-19 through municipal wastewater systems.[4] These excess deaths are often thought of in terms of the human loss, the relationships and families members we no longer possess, but there is also an economic side to these excess mortalities. According to data from the World Bank, in 2021 the average GDP per capita for someone living in the United States was $69,288.[5] Despite the shortcomings of Gross Domestic Product in this scenario it serves as a decent variable to describe the lost economic output due to these excess deaths. Doing the arithmetic of excess deaths to GDP per capita we can see that the United States has lost around $88.5 billion in total output due to excess deaths during the Covid-19 Pandemic. The costs of the pandemic can also be extrapolated out into the cost of vaccine development/deployment, the cost of shutdowns or lack thereof (i.e. lost work/lost spending/low risk areas being closed), the extra health spending for patients that did not need it or could have avoided hospitalization if vaccinated, the fiscal stimulus provided by our government, the lost values to retirement accounts, and the broader effects of inflation.

Individuals have a something to lose as well when it comes to contracting the disease of SARS-CoV-2. For many hourly workers, this sick time off results in lost income and many salaried workers are able to do some work from a home office. Both of these situations can have positive and negative outcomes; whether it's getting additional assistance from the enhanced unemployment benefits for the greater part of 2021, or working from home with poor internet connectivity or no dedicated workspace. These headaches for many potentially contributed to the difference in reported incidence versus estimated-actual incidence rates of Covid-19 within a population. A 2020 cross-sectional study published in the JAMA Internal Medicine Journal performed blood testing on a convenience sample in 10 geographic sites across the United States and found that based on seroprevalence there were 10 times more cases than was being reported.[6]

Covid-19

The idea of intertwining epidemiology and economics is relatively new with it first appearing in the early 1990's amidst the HIV/AIDS epidemic. Epidemiologists at the time realized that the disease was spread through one's decisions around sex, and reasoned that it must then be considered an endogenous variable within the Nash-Equilibrium, therefor linking this with economics as the outcomes could then be predicted.[1] Both Economics and Epidemiology however have influence from Utilitarianism in the form of, "doing the most good for the most amount of people" or cost-benefit analysis as both fields of study hope to find net positives in the outcomes of their decisions.[2] However, the SARS-CoV-2 Pandemic and its fallout, has brought extremely relevant and timely data to researchers in this field. From January 1st, 2020 until December 4th, 2022 there has been a centrally estimated 1,277,204 excess deaths relating from the Covid-19 pandemic, with a majority of deaths consisting of the disease.[3] Somewhat similar to John Snow discovering the vector for cholera through water pumps, epidemiologists were able to track community spread of Covid-19 through municipal wastewater systems.[4] These excess deaths are often thought of in terms of the human loss, the relationships and families members we no longer possess, but there is also an economic side to these excess mortalities. According to data from the World Bank, in 2021 the average GDP per capita for someone living in the United States was $69,288.[5] Despite the shortcomings of Gross Domestic Product in this scenario it serves as a decent variable to describe the lost economic output due to these excess deaths. Doing the arithmetic of excess deaths to GDP per capita we can see that the United States has lost around $88.5 billion in total output due to excess deaths during the Covid-19 Pandemic. The costs of the pandemic can also be extrapolated out into the cost of vaccine development/deployment, the cost of shutdowns or lack thereof (i.e. lost work/lost spending/low risk areas being closed), the extra health spending for patients that did not need it or could have avoided hospitalization if vaccinated, the fiscal stimulus provided by our government, the lost values to retirement accounts, and the broader effects of inflation.

Individuals have a something to lose as well when it comes to contracting the disease of SARS-CoV-2. For many hourly workers, this sick time off results in lost income and many salaried workers are able to do some work from a home office. Both of these situations can have positive and negative outcomes; whether it's getting additional assistance from the enhanced unemployment benefits for the greater part of 2021, or working from home with poor internet connectivity or no dedicated workspace. These headaches for many potentially contributed to the difference in reported incidence versus estimated-actual incidence rates of Covid-19 within a population. A 2020 cross-sectional study published in the JAMA Internal Medicine Journal performed blood testing on a convenience sample in 10 geographic sites across the United States and found that based on seroprevalence there were 10 times more cases than was being reported.[6]

Pandemics

Covid-19 presents a recent, measurable event where we can calculate outcomes from lockdowns/job losses/morbidity/mortality from the pandemic. Overarching lockdowns effective regardless of the incidence rate is costly by itself (healthy people not being able to work/consume).

October 2020

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124042/

Positive Analysis to use economics into epidemiological problems for epidemic policy ----- what will happen if we do x

Normative Analysis to evaluate preferred strategies for epidemics ------ is x the best choice of policy decisions?

Indirect effects such as schools closing and a parent having to forego work or reduce hours to take care of children.

Covid 19 governments put focus on not overwhelming health system over societal and economic consequences.

UK government said that between mitigation and suppression, mitigation would not work because health systems would become overwhelmed.

Used Observed deaths and Upper Bound Threshold deaths in across all United States from 2020 through the end of October 2022 and have shown there are around 770,000 excess deaths across the country in that time period. There were less deaths from car accidents, flu, and other transmissible diseases and instead Covid-19 was the majority player in deaths of 0.33% of the country.

Row Labels Sum of Observed Number Sum of Upper Bound Threshold
Alabama 525,413 500,604
Alaska 45,146 46,659
Arizona 639,617 589,839
Arkansas 316,653 308,601
California 2,651,582 2,526,564
Colorado 395,406 381,258
Connecticut 293,910 303,501
Delaware 92,768 96,999
District of Columbia 58,340 64,428
Florida 2,065,521 1,959,759
Georgia 869,041 805,341
Hawaii 105,806 116,886
Idaho 142,323 143,976
Illinois 1,014,328 982,845
Indiana 640,162 631,350
Iowa 283,332 290,751
Kansas 254,497 253,650
Kentucky 471,017 461,538
Louisiana 448,201 434,031
Maine 138,987 145,590
Maryland 474,954 484,806
Massachusetts 541,953 564,651
Michigan 938,583 904,242
Minnesota 424,045 427,383
Mississippi 318,013 298,242
Missouri 619,670 617,070
Montana 100,557 102,357
Nebraska 158,126 166,281
Nevada 264,979 261,336
New Hampshire 115,779 126,831
New Jersey 709,864 706,245
New Mexico 191,618 184,395
New York 950,476 929,109
New York City 554,388 506,736
North Carolina 935,671 908,598
North Dakota 67,257 72,816
Ohio 1,175,776 1,174,773
Oklahoma 386,517 374,999
Oregon 357,277 347,430
Pennsylvania 1,262,297 1,258,773
Puerto Rico 281,275 286,614
Rhode Island 95,716 103,776
South Carolina 506,424 480,816
South Dakota 78,232 83,772
Tennessee 746,008 716,535
Texas 2,094,335 1,929,453
Utah 189,225 189,210
Vermont 55,151 57,597
Virginia 680,144 658,449
Washington 554,052 549,222
West Virginia 224,619 218,511
Wisconsin 505,545 505,443
Wyoming 46,660 47,652
Grand Total 28,057,236 27,288,293
Difference
768,943

Data was downloaded from https://www.cdc.gov/nchs/nvss/vsrr/covid19/excess_deaths.htm and analyzed in Excel by the author. Data is reported by individual jurisdictions from 1/4/2020 to 10/29/2022. Upper bound threshold is generally considered the 'action' point in Epidemiology, the historical highest mortality values are pooled and calculated with one-sided confidence intervals [7].


Challenges to an economic and epidemiologic approach.

Policy????

"Doing the most good for the most amount of people" Economics and epidemiology have this in common.

Epidemiologists are more narrowly focused, minimizing adverse health outcomes.

Want net positive benefits

"Kaldor-Hicks Compensation Test" - do the winners win more than the losers lose

Lockdowns was more advantageous for old people and hurt young working aged people more

Cost benefit analysis (CBA)

"Elimination is not economic optimal"

Discounted as a strategy at the beginning of covid.

Economics, Epidemiology, and Pandemics: - DRAFT

https://sites.duke.edu/mcadams/files/2020/08/McAdams-Economic-Epidemiology.pdf

The idea of intertwining epidemiology and economics is relatively new, with it first appearing in the early 1990's amidst the HIV/AIDS epidemic. This was because the transmission of HIV/AIDs is based around how people were having sex which is considered an economic condition (Duke.edu).


https://www.japan.go.jp/tomodachi/2020/autumn2020/worlds_fastest_computer.html#:~:text=The%20Japanese%20supercomputer%20Fugaku%20has,amalgamation%20of%20Japanese%20technological%20prowess.

Japan's Fugaku super computer was responsible for finding drugs that would be able to combat Covid-19, before we had vaccines made. It was able to analyze 2,128 different drugs taking in all kinds of factors to narrow down the picks to less than two dozen, all in under 10 days which would have taken a normal supercomputer a year to do.

References

  1. ^ a b McAdams, David (08/27/2020). "Economic epidemiology in the wake of Covid-19" (PDF). Retrieved 11/18/2022. {{cite web}}: Check date values in: |access-date= and |date= (help)
  2. ^ a b Marseille, Elliot; Kahn, James G. (2019-04-03). "Utilitarianism and the ethical foundations of cost-effectiveness analysis in resource allocation for global health". Philosophy, Ethics, and Humanities in Medicine. 14 (1): 5. doi:10.1186/s13010-019-0074-7. ISSN 1747-5341. PMC 6446322. PMID 30944009.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  3. ^ a b "Estimated cumulative excess deaths during COVID". Our World in Data. Retrieved 2022-12-13.
  4. ^ a b Suthar, Surindra; Das, Sukanya; Nagpure, Ajay; Madhurantakam, Chaithanya; Tiwari, Satya Brat; Gahlot, Pallavi; Tyagi, Vinay Kumar (2021-02-15). "Epidemiology and diagnosis, environmental resources quality and socio-economic perspectives for COVID-19 pandemic". Journal of Environmental Management. 280: 111700. doi:10.1016/j.jenvman.2020.111700. ISSN 0301-4797.
  5. ^ a b "U.S. GDP Per Capita 1960-2022". www.macrotrends.net. Retrieved 2022-12-13.
  6. ^ a b "UpToDate". www.uptodate.com. Retrieved 2022-12-13.
  7. ^ Rakocevic, Bozidarka; et, al. (March 21, 2019). "Influenza surveillance: determining the epidemic threshold for influenza by using the Moving Epidemic Method (MEM), Montenegro, 2010/11 to 2017/18 influenza seasons". Euro Surveill. 24 (12) – via National Library of Medicine.