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U.S. Route 45 (US 45) is a major north-south United States highway and a border-to-border route, from Lake Superior to the Gulf of Mexico. A sign at the...

In the U.S. state of Alabama, U.S. Route 45 (US 45) is a 60-mile-long (97 km) north–south United States Highway in the east south central state of Alabama...

U.S. Highway 45 (US 45) runs north–south through the eastern and northern portions of the state of Wisconsin. Also called Highway 45, it runs from the...

US Highway 45 (US 45) is a part of the United States Numbered Highway System that runs from Mobile, Alabama, to the Upper Peninsula (UP) of the state...

U.S. Route 75 is a north–south U.S. Highway that runs 1,239 miles (1,994 km) in the central United States. The highway's northern terminus is located at...

special route of any U.S. Highway within the entire state of Mississippi, with the rest being signed as normal state highways. US 45 Alternate begins in...

U.S. Route 45 (US 45) in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport...

Dallas in favor of Interstate 45 (I-45), US 175 met US 75. US 175's western terminus is in Dallas at I-45. The highway's eastern terminus is in Jacksonville...

Highway 45 (often called Highway 45, STH-45 or WIS 45) was a number assigned to two different state highways in the U.S. state of Wisconsin: Highway 45...

U.S. Route 56 (US 56) is an east–west United States highway that runs for approximately 640 miles (1,030 km) in the Midwestern United States. US 56's...

Maryland Route 45 (MD 45) is a state highway in the U.S. state of Maryland. Known for most of its length as York Road, the state highway runs 30.06 miles...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside of...

Arkansas Highway 45 (AR 45) is a designation for three state highways in Northwest Arkansas. One segment of 26.97 miles (43.40 km) runs from Highway 96 north...

U.S. Route 54 (US 54) is an east–west United States Highway that runs northeast–southwest for 1,197 miles (1,926 km) from El Paso, Texas, to Griggsville...

U.S. Route 85 (US 85) is a 1,479-mile-long (2,380 km) north–south United States Highway that travels in the Mountain and Northern Plains states of the...

U.S. Route 111 (US 111) was a U.S. Highway that extended from Baltimore, Maryland north to the Harrisburg, Pennsylvania area. It replaced part of the Susquehanna...

U.S. Route 98 (US 98) is an east–west United States Highway in the Southeastern United States that runs from western Mississippi to southern Florida....

U.S. Route 61 or U.S. Highway 61 (U.S. 61) is a major United States highway that extends 1,400 miles (2,300 km) between New Orleans, Louisiana and the...

at US Highway 10 (US 10) and WIS 96 southeast of Fremont; its northern terminus is at US 45 in Marion. The highway begins at an intersection with US 10...

U.S. Route 40 or U.S. Highway 40 (US 40), also known as the Main Street of America (a nickname shared with U.S. Route 66), is a major east–west United...