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There is a page named "Thymidine kinase 2, mitochondrial" on Wikipedia
- Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene. This gene encodes a deoxyribonucleoside kinase that specifically...1 KB (193 words) - 14:52, 20 January 2024
- Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21. It can be...103 KB (11,263 words) - 23:00, 25 July 2024
- Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase. Two forms of this protein have been identified in animal cells, one in cytosol...10 KB (1,226 words) - 10:09, 24 January 2024
- patient prognosis. Patients with mutations in the thymidine kinase gene may have a certain type of mitochondrial DNA depletion syndrome, a disease that leads...34 KB (3,807 words) - 19:38, 18 August 2024
- insight into mitochondrial DNA depletion syndrome in two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes". Molecular...23 KB (2,562 words) - 19:54, 23 August 2024
- Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC 2.7.1.21 that catalyzes...83 KB (9,990 words) - 04:54, 15 July 2024
- Y, Eriksson S, Elpeleg O (November 2001). "Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy". Nature Genetics. 29 (3): 342–4...21 KB (2,519 words) - 01:02, 3 December 2023
- includes deoxycytidine kinase (cytosolic) as well as the two mitochondrial enzymes deoxyguanosine kinase and thymidine kinase 2 in humans. The base specificity...3 KB (354 words) - 05:31, 24 July 2024
- (June 2010). "Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity". Nucleosides, Nucleotides & Nucleic Acids...48 KB (4,933 words) - 14:27, 15 August 2024
- Cell synchronization (section Double thymidine block)The process begins with a treatment with thymidine, washing of the culture, followed by another thymidine treatment. Hydroxyurea decreases the production...16 KB (2,132 words) - 20:44, 30 November 2023
- when this oxidized derivative of deoxyguanosine was inserted into the thymidine kinase gene in a chromosome within human lymphoblastoid cells in culture....25 KB (2,763 words) - 21:16, 13 April 2024
- with the mitochondrial thymidine kinase, as part of the thymidine (dTTP)/dTMP substrate cycle. Since excess dTTP leads to aberrant mitochondrial DNA replication...7 KB (818 words) - 21:00, 13 October 2022
- Glutathione S-transferase (redirect from EC 2.5.1.12)"Deoxyribonucleoside kinases in two aquatic bacteria with high specificity for thymidine and deoxyadenosine". FEMS Microbiology Letters. 331 (2): 120–7. doi:10...38 KB (4,286 words) - 01:59, 22 June 2024
- DTYMK (category Genes on human chromosome 2)Yamaguchi Y, et al. (1989). "Co-purification of thymidylate kinase and cytosolic thymidine kinase from human term placenta by affinity chromatography". Biochim...4 KB (493 words) - 08:27, 17 October 2022
- Thymidylate synthase (redirect from EC 2.1.1.45)(EC 2.1.1.45) is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). Thymidine is one...16 KB (1,902 words) - 00:29, 10 March 2024
- the size of dNTP pools in cells, in conjunction with the cytosolic thymidine kinases, as part of the dNTP substrate cycle. The enzyme is ubiquitously expressed...12 KB (1,438 words) - 10:55, 11 April 2024
- Purine nucleoside phosphorylase (redirect from EC 2.4.2.1)such as ATP or PRPP. Thymidine can be phosphorylated by thymidine kinase (TK). Uridine can be phosphorylated by uridine kinase (UK). Cytidine can be...14 KB (1,511 words) - 15:37, 26 August 2023
- DGUOK (category Genes on human chromosome 2)insight into mitochondrial DNA depletion syndrome in two patients with novel mutations in the deoxyguanosine kinase and thymidine kinase 2 genes". Mol...8 KB (1,023 words) - 22:39, 18 August 2023
- This phosphorylation step is carried out by cellular kinase enzymes. NRTIs can induce mitochondrial impairment that leads to a number of adverse events...26 KB (2,918 words) - 04:25, 3 July 2024
- affinity for zidovudine to thymidine kinase (the enzyme responsible for the first phosphorylation) is similar to that of thymidine, whereas the affinity for...33 KB (3,234 words) - 14:14, 3 July 2024
- of the action of thymidine kinase in the cell: thymidine triphosphate (TTP), the product of the further phosphorylation of thymidine, acts as an inhibitor