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The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune...

cells which produce interferon gamma and lymphotoxin alpha, TH2 cells which produce IL-4, IL-5, and IL-13. A third category called T helper 17 cells (TH17)...

induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a...

CD4+ T cells specialized in providing help to B cells to proliferate and to undergo class switch recombination and somatic hypermutation. Th2 cells, through...

Th17 cell lineage appears to be one of the three major subsets of effector T cells, as these cells are involved in regulation of neutrophils, while Th2 cells...

antitumor immunity role of CD4+ T cells has grown substantially since the late 1990s. CD4+ T cells (mature T-helper cells) play an important role in modulating...

IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosinophils and nuocytes. Interleukin-13...

of Th2 cells. They express characteristic surface markers and receptors for chemokines, which are involved in the distribution of lymphoid cells to specific...

(Th2)-associated cytokines (e.g., IL-4). IL33 is a ligand for ST2 (IL1RL1), an IL-1 family receptor that is highly expressed on Th2 cells, mast cells and...

variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give...

development of T helper type 2(Th2) cells. IL-4 is important for the differentiation of naïve CD4-T cells into mature Th2 type cells; as well as for Immunoglobulin...

Because parasitic worms often induce Th2 cells and lead to suppressed Th1 cells, problems arise when Th1 cells are needed. Such cases occur with viral...

dendritic cells. Th2 cells and ILC2 cells secrete IL-4, IL-5 and IL-13. IL-4 further drives CD4+ T cell differentiation towards the Th2 subtype and induces...

Th1 and Th2 cells. Th3 cells have different cytokine requirements for their growth from CD25+CD4+ Treg cells. The survival of CD25+CD4+ Treg cells is dependent...

lymphoid cells (ILCs), particularly Group 2 ILCs as well as for the development of T helper cells,(Th cells), particularly Th2 cells. Group 2 ILCs and Th2 cells...

antigen-presenting cells (APCs) and T helper cells (Th1 cells), but upregulates interleukin 4, interleukin 10, and interleukin 13 by Th2 cells. This results...

(APCs) like dendrites. They divide into memory cells, TH1, TH17, and TH2 cells, to name a few. Memory cells are made solely for the purpose of having a template...

presence of these cells, which confirm the important physiologic function for these cells during worm infection. Activation of Th2 cells is an important...

immunological organ containing a wide range of cytokine-producing cells. Both Th1 and Th2 cells are involved in the pathophysiology of TH and RT conditions...

Suplatast tosilate (INN) is an inhibitor of cytokine T helper cells. Overstimulation of these Th2 cells can lead to an allergic reaction, so the drug is used...