Talk:Polycythemia vera
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Prognosis
What is the prognosis? Linuxo (talk) 17:54, 2 June 2018 (UTC)
I
I have PV. The following part may need review:
The tendency to avoid chemotherapy if possible, especially in young patients, is due to research indicating increased risk of transformation to AML, and while hydroxyurea is considered safer in this aspect, there is still some debate about its long-term safety.
I am pretty sure I remember that my oncologist told me that the studies linking hydroxyurea to AML are suspect, and that newer studies indicate it might even reduce the incidence of progression to AML.
- We need a reliable source that says this. Can you find one? WhatamIdoing (talk) 05:35, 13 April 2008 (UTC)
- Too late. My oncologist retired. I'll ask the new one if I remember to. But I note there is no reliable source cited for the bit I objected to. "Increased risk of transformation to AML" ought not to be tossed off lightly. People could balk at the treatment they need. Jive Dadson (talk) 06:31, 10 August 2009 (UTC)
External links
Wikipedia's external links policy and the specific guidelines for medicine-related articles do not permit the inclusion of external links to non-encyclopedic material, particularly including: patient support groups, personal experience/survivor stories, internet chat boards, e-mail discussion groups, recruiters for clinical trials, healthcare providers, fundraisers, or similar pages.
Wikipedia is an encyclopedia, not an advertising opportunity or a support group for patients or their families. Please do not re-insert links that do not conform to the standard rules.
External links are not required in Wikipedia articles. They are permitted in limited numbers and in accordance with the policies linked above. If you want to include one or more external links in this article, please link directly to a webpage that provides detailed, encyclopedic information about the disease. Thanks, WhatamIdoing (talk) 05:35, 13 April 2008 (UTC)
- I put the support group link back in before I read this. The Wikipedia rules do a disservice to those of us who have the disease. The support groups have more and more up-to-date information than the wiki page. I will remove it, but reluctantly. Jive Dadson (talk) 22:06, 16 December 2008 (UTC)
Hydroxyurea
My doctor prescribed hydroxyurea to bring down my platelet count. The article says only that it is prescribed to bring down the hemocrit. Phelbotomies alone kept my hemocrit within bounds, but not platelets. Jive Dadson (talk) 22:06, 16 December 2008 (UTC)
Polycythemia rubra vera
Why does that forward to the article for polycythemia instead of this article? 24.99.86.24 (talk) 19:23, 10 January 2009 (UTC)
Phlebotomy and hydroxyurea
I did a little editing about when hydroxyurea is indicated. I have PV, and I take hydroxyurea daily. It was not indicated (for me) due to too many blood-lettings being necessary. The oncologist (now retired) said that blood-letting alone does not control excessive platelet production. Around here, (California USA), the normal regimen is daily maintenance with hydroxyurea with phlebotomies only when indicated by blood tests.
I do not have all the references and citations I would need to add that information, so I only removed the assertions that I know to be incorrect because of my personal counter-example and others I see at the clinic. Again, I urge people to edit this Wiki page like walking on eggs. Being diagnosed with an incurable blood disease can put a person into a panic. Be careful.
I see someone changed all the occurrences of "phlebotomy" with "venesection." I was not familiar with the word "venesection." (Neither is my spell-checker.) In these parts, (California USA), it is always called "phlebotomy." From the roots, both words literally mean "vein-cutting." I put in one reference to "phlebotomy." Jive Dadson (talk) 01:58, 18 December 2010 (UTC)
External links modified
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Cheers. —cyberbot IITalk to my owner:Online 10:25, 19 October 2015 (UTC)
Review
doi:10.1111/bjh.13812 JFW | T@lk 09:25, 27 October 2015 (UTC)
Relation between ESR(Erythrocyte Sedimentation Rate) and Zeta potential(ζ, in mV)in Polycythemia: ζ decrease is due to higher RBC aggregation (Erythrocyte Aggregation, EA). ESR is directly linked to EA. Higher ESR, higher EA. On the other hand lower EA means higher ζ. So when ESR decreases is because EA decreases and consequently ζ increases. The opposite is written in the article. I believe that ζ increase is clear due to higher hematocrit (more particles, more electrical charge). — Preceding unsigned comment added by Antonio valadão (talk • contribs) 19:47, 7 May 2018 (UTC)