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Germline Mosaicism depends on the stage of development the embryo is in -Problems – it is difficult to detect germline mosaicism because mutations would not...

article! First paragraph: You describe the attempts to edit the human germline as “rather unsuccessful”, but could you elaborate on this? It seems like...

Waller M., Rosenstiel P., Grossniklaus U. 2014. Apomictic and Sexual Germline Development Differ with Respect to Cell Cycle, Transcriptional, Hormonal and...

models explaining how restriction arose are the germline model and the selection model. The germline model suggests that MHC restriction is a result of...

aren't needed, making sections more cohesive; especially in the human germline engineering section. PGD section - improving language, explaining the process...

https://web.archive.org/web/20070813010925/http://www.germline.ucla.edu/ to http://www.germline.ucla.edu/ Added archive https://web.archive...

the germline “micronucleus”." instead of "Ciliates are unicellular eukaryotes with two types of nuclei: the somatic “micronucleus” and the germline “macronucleus”...

mechanisms as found in B cells. Like B cells they start their development with a germline DNA canvas and both sets of cells will mature into lymphocytes...

genetically engineering the human germline, writing “scientists should avoid even attempting, in lax jurisdictions, germline genome modification for clinical...

"Somatic cells are any cells forming the body of an organism, as opposed to germline cells." This sentence does not make sense. If somatic cells form the organism...

365-373. # Perrimon, N. (1984) Clonal analysis of dominant female sterile, germline- dependent mutations in Drosophila melanogaster. Genetics 108, 927-939...

Chalmel F, Primig M (2010). "GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle". Database (Oxford). 2010: baq030...

2016 (UTC) Yes!! Since the discovery in 1990 that LFS was caused by the germline (born with it in every cell) variation of the tumor suppressor gene, TP53...

disc epithelial cells" Development 130 (9): 1735-47 PMID: 12642480. Tworzydlo W, Kloc M, and Bilinski SM (2009) "Female germline stem cell niches of earwigs...

Somatic mutations have important and distinct traits/effects/roles from germline mutations and mutations as a whole. Mutation is already a long article...

a good analogy with antigenic imprinting? Surely, it’s not “original” (germline) in any meaningful sense? If we wanted to reach to a more appropriate doctrine...

remove “that are mentioned above,” last sentence doesn’t make sense "Germline" section – is (4) supposed to be a reference citation? "Current research"...

into early embryos. Resulting animals with the genetic change in their germline cells can then often pass the gene knockout to future generations. The...

argued that since cloning and germline genetic manipulation of animals are error-prone and inherently disruptive of development, it would be unethical to...