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definition of a stem cell requires that it possesses two properties: Self-renewal: the ability to go through numerous cycles of cell growth and cell division...

hematopoietic stem cells that are multipotent and capable of extensive self-renewal. Hematopoietic stem cells give rise to different types of blood cells, in lines...

to cell signals. Local signals regulate the self-renewal of spermatogonial stem cells (SSCs). Around 50% of the SSC population undergo self-renewal to...

regulating the embryonic stem cell cycle. Due to their plasticity and potentially unlimited capacity for self-renewal, embryonic stem cell therapies have been...

populations in the adult are indeed stem cells. To ensure self-renewal, stem cells undergo two types of cell division (see Stem cell division and differentiation...

self-renewal or differentiation to form new tissues. Several factors are important to regulate stem-cell characteristics within the niche: cell–cell interactions...

cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types. Such cells are hypothesized...

many cell types, whereas a pluripotent stem cell can give rise to all types. ESCs have the characteristic properties of a stem cell: self-renewal and differentiation...

involved in the self-renewal of undifferentiated embryonic stem cells. As such, it is frequently used as a marker for undifferentiated cells. Oct-4 expression...

involved. Peritubular myoid cells play a crucial role in the self-renewal and maintenance of the spermatogonial stem cell (SSC) population. For those...

pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC...

identified a series of key stem cell self-renewal regulators, revealing several important principles. First, stem cell self-renewal is mechanistically distinct...

many as 1 in 100 cells collected during amniocentesis are pluripotent mesenchymal stem cells. MSCs have a great capacity for self-renewal while maintaining...

"Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal". Blood. 124 (21): 650. doi:10.1182/blood.V124.21.650.650....

fields such as: Stem cell self-renewal Lineage specification Cancer cell phenotype Fibrosis Hepatocyte function Mechanosensing Cell culture in three...

regulator of XCI or embryonic stem cell self-renewal. The Bmi1 polycomb ring finger protein promotes neural stem cell self-renewal. Murine null mutants in PRC2...

differentiation is the process in which a stem cell changes from one type to a differentiated one. Usually, the cell changes to a more specialized type. Differentiation...

pluripotent stem cells, commonly abbreviated as iPS cells or iPSCs, are a type of pluripotent stem cell artificially derived from a non-pluripotent cell, typically...

Stem cell markers are genes and their protein products used by scientists to isolate and identify stem cells. Stem cells can also be identified by functional...

containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms...