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In molecular biology, the Signal Peptide Peptidase (SPP) is a type of protein that specifically cleaves parts of other proteins. It is an intramembrane...

signal proteinase, leader peptidase, leader peptide hydrolase, leader proteinase, signal peptidase, pilin leader peptidase, SPC, prokaryotic signal peptidase...

A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence...

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides...

A-chain, a C-peptide, a B-chain, and a signal sequence. The signal sequence is cleaved from the N-terminus of the peptide by a signal peptidase, leaving proinsulin...

Signal peptidases are enzymes that convert secretory and some membrane proteins to their mature or pro forms by cleaving their signal peptides from their...

activity of the proteolytic enzyme dipeptidyl peptidase-4 (DPP-4). Specifically, DPP-4 cleaves the peptide bond between Ala8-Glu9 resulting in the abundant...

Signal peptide peptidase 3, also known as UNQ1887, is a human gene. GRCh38: Ensembl release 89: ENSG00000157837 – Ensembl, May 2017 GRCm38: Ensembl release...

(November 1999). "Dipeptidyl-peptidase IV (CD26)--role in the inactivation of regulatory peptides". Regulatory Peptides. 85 (1): 9–24. doi:10.1016/S0167-0115(99)00089-0...

Signal peptidase II (EC 3.4.23.36, premurein-leader peptidase, prolipoprotein signal peptidase, leader peptidase II, premurein leader proteinase) is an...

Signal peptide peptidase-like 2B, also known as SPPL2B, is a human gene. This gene is a member of the signal peptide peptidase-like protease (SPPL) family...

be addressed. The protein encoded by the M13/HM13 gene is the signal peptide peptidase (SPP), an ER-resident intramembrane protease. SPP localizes to...

extended the lifespan by approximately one month. Glucagon-like peptide-1 Dipeptidyl peptidase-4 GRCh38: Ensembl release 89: ENSG00000112164 – Ensembl, May...

JY, Koh SK, Jeon MH, Chung D, Lee YW, Chae SK (May 2016). "The signal peptide peptidase SppA is involved in sterol regulatory element-binding protein cleavage...

Signal peptide peptidase-like 2A, also known as SPPL2A, is a human gene. This gene is a member of the signal peptide peptidase-like protease (SPPL) family...

Asparagine peptide lyase are one of the seven groups in which proteases, also termed proteolytic enzymes, peptidases, or proteinases, are classified according...

different isoforms. PreproGRP begins with signal peptidase cleavage to generate the pro-gastrin-releasing-peptide (proGRP), which is then processed by proteolytic...

nonamer peptide epitope derived from the signal sequence of classical MHC class I molecules, which is generated by the sequential action of signal peptide peptidase...

GIP are rapidly inactivated by the enzyme dipeptidyl peptidase-4 (DPP-4). Glucagon-like peptide (GLP) agonists bind to a membrane GLP receptor. As a consequence...

released from the membrane of the endoplasmic reticulum (ER) by the signal peptide peptidase and trimmed by the cytosolic proteasome. Upon transport into the...