SLC38A5

SLC38A5
Identifiers
Aliases	SLC38A5, JM24, SN2, SNAT5, pp7194, solute carrier family 38 member 5
External IDs	OMIM: 300649; MGI: 2148066; HomoloGene: 24917; GeneCards: SLC38A5; OMA:SLC38A5 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	48,470,260 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	8,146,418 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; bone marrow cells; ; stromal cell of endometrium; ; upper lobe of left lung; ; C1 segment; ; mucosa of transverse colon; ; left lobe of thyroid gland; ; ganglionic eminence; ; right lobe of thyroid gland; ; right frontal lobe;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; cumulus cell; ; tibiofemoral joint; ; lumbar subsegment of spinal cord; ; left lung lobe; ; blood; ; pyloric antrum; ; Ileal epithelium; ; perirhinal cortex; ; medial ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	glycine transmembrane transporter activity; amino acid transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	amino acid transport; glycine transport; amino acid transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	92745
	209837
	ENSG00000017483
	ENSMUSG00000031170
	Q8WUX1
	Q3U1J0
	NM_033518
	NM_172479
	NP_277053
	NP_766067
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 38 member 5 is a protein that in humans is encoded by the SLC38A5 gene. ^[5]

Function

The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000017483 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031170 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Solute carrier family 38 member 5". Retrieved 2017-10-07.