Propagermanium
Appearance
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Names | |
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IUPAC name
3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
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Other names
proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.032.533 |
EC Number |
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KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C6H10O7Ge2 | |
Molar mass | 339.4222 g/mol |
Hazards | |
GHS labelling:[1] | |
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Warning | |
H315, H319, H335 | |
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium[2] that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.
The compound was first synthesized in 1967 at the Asai Germanium Research Institute[3] in Japan. It is a water-soluble organogermanium compound used as raw material in nutritional supplements. The compound displays low toxicity in studies with rats.[4]
References
- ^ "Bis (2-Carboxyethylgermanium)sesquioxide". pubchem.ncbi.nlm.nih.gov.
- ^ M.P. Egorov, P.P. Gaspar (1994), Germanium: Organometallic chemistry in Encyclopedia of Inorganic Chemistry. John Wiley & Sons ISBN 0-471-93620-0
- ^ "Asai Germanium Japan". Asai Germanium Japan. Retrieved 2022-02-04.
- ^ Doi, Yuko; et al. (2017). "No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice". Fundamental Toxicological Sciences. 4 (3): 137–150. doi:10.2131/fts.4.137.