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There is a page named "Positive allosteric modulation" on Wikipedia
- both be called receptor ligands. Allosteric modulators can be 1 of 3 types either: positive, negative or neutral. Positive types increase the response of...19 KB (2,293 words) - 20:29, 8 July 2024
regulatory sites can each produce positive allosteric modulation, potentiating the activity of GABA. Diazepam is a positive allosteric modulator at the benzodiazepine...37 KB (4,437 words) - 20:55, 13 August 2024- GABAB receptor (section Positive Allosteric Modulators)Heid J, Hofstetter K, Froestl W, et al. (November 2001). "Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors...16 KB (1,564 words) - 20:19, 25 March 2024
pharmacology, GABAA receptor positive allosteric modulators, also known as GABAkines or GABAA receptor potentiators, are positive allosteric modulator (PAM) molecules...31 KB (3,522 words) - 00:57, 6 June 2024
Malysz J (September 2007). "Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes". Molecular Pharmacology...26 KB (2,626 words) - 17:23, 19 June 2024
Cannabinoid receptor 1 (section Allosteric agonist)Navarro HA, Howard JL, Pollard GT, Carroll FI (April 2009). "Positive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective...40 KB (4,148 words) - 13:59, 6 August 2024
Sanna L.; Stompor, Monika; Uusi-Oukari, Mikko (February 2019). "Positive allosteric modulation of native and recombinant GABAA receptors by hops prenylflavonoids"...25 KB (2,807 words) - 18:31, 26 April 2024
5-HT1A receptor (section Allosteric modulators)Naing S, Hoffman AF, Baumann MH, Lupica CR, Shi L (2020). "Positive Allosteric Modulation of the 5-HT1A Receptor by Indole-Based Synthetic Cannabinoids...58 KB (6,181 words) - 22:24, 4 August 2024
principal mechanism of action of barbiturates is believed to be positive allosteric modulation of GABAA receptors. Examples include amobarbital, pentobarbital...43 KB (4,540 words) - 03:27, 25 June 2024
"Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes"...28 KB (3,221 words) - 02:58, 29 July 2024
phase inhibition) Blockage of acid-sensing ion channels (ASICs) Positive allosteric modulation of KCNQ- and BK-potassium channels (diclofenac opens these channels...58 KB (5,599 words) - 23:32, 10 June 2024
"Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes"...5 KB (456 words) - 07:37, 6 January 2024
KCNQ2/3 (Kv7.2/Kv7.3) voltage-gated potassium channels via positive allosteric modulation. The opening of these voltage-gated potassium channels, which...6 KB (525 words) - 13:03, 9 July 2024
CGP-7930 (category GABAB receptor positive allosteric modulators)Heid J, Hofstetter K, Froestl W, et al. (November 2001). "Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors...7 KB (555 words) - 01:12, 4 January 2024
Anabolic steroid (section GABAA receptor modulation)3α-hydroxysteroid dehydrogenase (3α-HSD)), is a neurosteroid that acts via positive allosteric modulation of the GABAA receptor. Testosterone, via conversion into DHT...209 KB (21,563 words) - 23:23, 7 August 2024
(June 2018). "Reversal of Nicotine Withdrawal Signs Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Male Mice". Nicotine...9 KB (829 words) - 15:19, 6 June 2024
Pharmacology of ethanol (category GABAA receptor positive allosteric modulators)receptor positive allosteric modulation. However, other ion channels are involved in its effects as well. Although ethanol exhibits positive allosteric binding...96 KB (10,550 words) - 10:57, 20 July 2024
Sarro, G; Simonyi, A; Van Luijtelaar, G; Nicoletti, F (2008). "Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous...29 KB (3,692 words) - 22:44, 12 December 2023
effects of methaqualone and etomidate are mediated through GABBR3 positive allosteric modulation. The GABRB3 gene is located on the long arm of chromosome 15...24 KB (3,081 words) - 01:59, 4 March 2023- Christopoulos A, Lazareno S, Birdsall NJ, Bymaster FP, Felder CC (2008). "Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia"...16 KB (1,853 words) - 03:12, 24 November 2022
- it leads to pain relief. Research is also done in the usage of positive allosteric modulators, PAMs, that increase the odds a signaling molecule, in