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There is a page named "PD-1 and PD-L1 inhibitors" on Wikipedia
- PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitor anticancer drugs that block the activity of PD-1 and PDL1 immune checkpoint proteins...31 KB (3,266 words) - 05:29, 20 May 2024
- Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by...24 KB (3,052 words) - 08:26, 20 August 2024
- PD-1 inhibitors, a new class of drugs that block PD-1, activate the immune system to attack tumors and are used to treat certain types of cancer. PD-1...39 KB (5,010 words) - 05:27, 17 August 2024
- Cancer immunotherapy (redirect from PD-1 inhibitor)other proteins. Checkpoint inhibitors (CTLA-4, PD-1, and PD-L1) operate by this mechanism. Briefly, checkpoint inhibitors are proteins that normally help...89 KB (10,338 words) - 14:21, 16 July 2024
- checkpoint inhibitors target the molecules CTLA4, PD-1, and PD-L1. PD-1 is the transmembrane programmed cell death 1 protein (also called PDCD1 and CD279)...21 KB (2,093 words) - 18:53, 25 January 2024
- Atezolizumab (section Society and culture)reduced appetite, diarrhea, and cough. Atezolizumab was the first PD-L1 inhibitor approved by the U.S. for bladder cancer. Food and Drug Administration (FDA)...43 KB (4,164 words) - 02:04, 16 July 2024
- Pembrolizumab (category Wikipedia articles incorporating text from the United States Department of Health and Human Services)chemotherapy (for all PD-L1, a PD-1 receptor ligand, levels) or by itself as a first-line treatment if the cancer expresses (≥ 1%) PD-L1 and the cancer has no...79 KB (7,328 words) - 01:51, 16 July 2024
- Nivolumab (section Pregnancy and breastfeeding)respond well to PD-1 inhibitors. PD-L1 levels appeared to be dynamic and modulated by several factors, and efforts to correlate PD-L1 levels before or...47 KB (4,870 words) - 15:14, 3 August 2024
- Enfortumab vedotin (section Society and culture)previously received a programmed death receptor-1 (PD-1) or programmed death ligand 1 (PD-L1) inhibitor and a platinum-containing chemotherapy. Results of...14 KB (1,039 words) - 01:30, 18 May 2024
- programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). Formation of a PD-1/PD-L1 receptor/ligand complex...15 KB (1,447 words) - 05:05, 1 July 2024
- BeiGene (section Research and development)a PD-1 antibody or PD-L1 inhibitor that prevents cancer tumors from evading the immune system. Tislelizumab is being developed as a monotherapy and for...25 KB (2,299 words) - 17:57, 21 May 2024
- Sacituzumab govitecan (section Society and culture)chemotherapy and either a programmed death receptor-1 (PD-1) or a programmed death-ligand 1 (PD-L1) inhibitor. It is also indicated for the treatment of people...30 KB (2,408 words) - 02:24, 16 July 2024
- nausea or vomiting when compared to carboplatin treatment. PD‐L1 inhibitors are more effective and lead to longer survival with fewer side effects compared...51 KB (5,338 words) - 00:03, 27 August 2024
- Currently approved checkpoint inhibitors block CTLA4, PD-1 and PD-L1. For the related basic science discoveries, James P. Allison and Tasuku Honjo won the Tang...31 KB (3,467 words) - 01:27, 25 June 2024
- treatments. The first interim results show promise for combined TIGIT and PD-L1 co-blockade in solid cancer patients. Mechanistically, research has shown...18 KB (2,103 words) - 17:00, 19 July 2024
- microtubulin inhibitors monomethyl auristatin E (MMAE), monomethyl auristatin F (MMAF) and mertansine, DNA binder calicheamicin and topoisomerase 1 inhibitors SN-38...41 KB (4,305 words) - 11:56, 24 August 2024
- Tislelizumab (section Society and culture)at least two prior therapies; and to treat people with locally advanced or metastatic urothelial carcinoma with PD-L1 high expression whose disease progressed...15 KB (955 words) - 15:50, 6 August 2024
- receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway. The most common side effects include fatigue, rash, diarrhea, musculoskeletal pain, and nausea. In...13 KB (1,060 words) - 05:46, 18 July 2024
- correlation between treatment response rate and TMB level in patients treated with anti-PD-1 or anit-PD-L1 (types of ICIs). Additionally, it has been reported...28 KB (3,499 words) - 21:17, 15 February 2024
- cysticercosis” examined the sex-associated expression of MHC-II, CD80, CD86, PD-L1, and PD-L2 expressed on peritoneal F4/80 macrophages of BALB/c mice exposed
- a rapidly evolving field. CAR-T cell therapy and immune checkpoint inhibitors like PD-1/PD-L1 inhibitors showed promising results in various types of