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Members of the Non-Selective Cation Channel-2 (NSCC2) Family (TC#1.A.15) have been sequenced from various yeast, fungal and animals species including...

cation (Na+, K+ and Ca2+) channel that is activated by Ca2+, while polycystin-2 has been characterized as a Ca2+-permeable cation-selective channel....

The transmembrane cation channel superfamily was defined in InterPro and Pfam as the family of tetrameric ion channels. These include the sodium, potassium...

ion channels or CNG channels are ion channels that function in response to the binding of cyclic nucleotides. CNG channels are nonselective cation channels...

2022). "Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel". Nature Communications. 13 (1): 1416. doi:10...

mechanism of potassium channel selectivity remains under continued debate. The carbonyl oxygens are strongly electro-negative and cation-attractive. The filter...

proton channels Non-selective cation channels: These non-selectively allow many types of cations, mainly Na+, K+ and Ca2+, through the channel. Most transient...

groups of the channel protein. The diameter of the selectivity filter is ideal for the potassium cation, but too big for the smaller sodium cation. Hence the...

superfamily of cation channels. They are classified into 2 types: In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible...

control over ion flow. Some cation channels allow calcium as well as other cations to pass through the membrane. Calcium channels can participate in the creation...

The Pseudomonas syringae HrpZ Cation Channel (HrpZ) Family (TC# 1.C.56) is a member of the RTX-toxin superfamily. The Harpin-PSS (HrpZ; TC# 1.C.56.1.1)...

they are molecular sensing, non-selective cation channels that have six transmembrane segments, however, each sub-family is unique and shares little structural...

thirst). The channels vary in selectivity for the permeating ions from nonselective between anions and cations in bacteria, to cation selective allowing passage...

acts as a selective agonist at these receptors. When the NMDA receptor is activated by the binding of two co-agonists, the cation channel opens, allowing...

potential Ca2+ channel (TRP-CC) family (TC# 1.A.4) is a member of the voltage-gated ion channel (VIC) superfamily and consists of cation channels conserved...

Ca2+ Release-activated Ca2+ (CRAC) Channel (CRAC-C) Family (TC# 1.A.52) is a member of the Cation Diffusion Facilitator (CDF) Superfamily. These proteins...

The transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein...

effects by non-selectively blocking voltage-gated sodium channels. Nav1.7, as well as Nav1.3, Nav1.8, and Nav1.9, are the specific channels that have been...

epithelial sodium channel (ENaC), (also known as amiloride-sensitive sodium channel) is a membrane-bound ion channel that is selectively permeable to sodium...

humans is encoded by the TRPM5 gene. TRPM5 is a calcium-activated non-selective cation channel that induces depolarization upon increases in intracellular calcium...