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Kv7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. It's mutation causes Long QT syndrome, Kv7...

Voltage-gated potassium channels (VGKCs) are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential...

primarily known for modulating the cardiac and epithelial Kv channel alfa subunit, KCNQ1. KCNQ1 and KCNE1 form a complex in human ventricular cardiomyocytes...

Abogadie FC, Jentsch TJ, Brown DA (February 2000). "Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors"...

PMID 16267222. Rivas, A; Francis, H. W (2005). "Inner ear abnormalities in a Kcnq1 (Kvlqt1) knockout mouse: A model of Jervell and Lange-Nielsen syndrome"...

Selyanko AA, Hadley JK, Wood IC, et al. (2000). "Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors"...

KCNQ genes encode family members of the Kv7 potassium channel family. These include Kv7.1 (KCNQ1) - KvLQT1, Kv7.2 (KCNQ2), Kv7.3 (KCNQ3), Kv7.4 (KCNQ4)...

splay opening the channel. All members of the Kir super-family of potassium channels are thought to be directly gated by PIP. Kv7 channels: PIP2 binds to...

suppress potassium channel function, but this varies depending on the channel subtype. KCNE4 strongly inhibits the KCNQ1 potassium channel, which is...

can travel into or out of cell through leak channels, including the inwardly rectifying potassium channel. Therefore, the resting membrane potential is...

for the potassium channel beta subunit MinK which, in conjunction with the alpha subunit encoded by KCNQ1, is responsible for the potassium current IKs...

prevention cohorts (CARE and PROVE IT-TIMI 22). Voltage-gated potassium channel KCNE1 KCNE3 KCNQ1 GRCh38: Ensembl release 89: ENSG00000159197 – Ensembl, May...

transmembrane cation channel superfamily was defined in InterPro and Pfam as the family of tetrameric ion channels. These include the sodium, potassium, calcium,...

KCNE family of voltage-gated potassium (Kv) channel ancillary or β subunits. KCNE3 is best known for modulating the KCNQ1 Kv α subunit, but it also regulates...

involved in long QT syndrome. Mutations in the KCNQ1 gene that codes for the voltage-gated potassium channel KV7.1 have been implicated in cardiac arrhythmias...

the potassium channel beta subunit MinK. This subunit, in conjunction with the alpha subunit encoded by KCNQ1, is responsible for the potassium current...

and KCNQ1 genes. The proteins produced by these two genes work together to form a potassium channel that transports positively charged potassium ions...

of ion channels, abbreviated Kv7.2. The KCNQ gene subfamily consists of five members (KCNQ1–5), all encoding voltage-gated potassium (K+) channel subunits...

channels within heart cells. It appears to be inherited in an autosomal dominant pattern. Some genetic variants cause an increased flow of potassium out...

also have a K+ channel which is formed of two subunits, the KCNE1 regulatory protein and the KCNQ1 channel proteins.[8] This channel provides the pathway...