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An immunoproteasome is a type of proteasome that degrades ubiquitin-labeled proteins found in the cytoplasm in cells exposed to oxidative stress and proinflammatory...

But in thymus we can also find another type of specific proteasome, immunoproteasome, which is present in thymocytes, dendritic cells and medular thymic...

histocompatibility complex molecules, MHC I and MHC II, and increase immunoproteasome activity. All interferons significantly enhance the presentation of...

This protein has a major role in the immune system as part of an immunoproteasome that is primarily induced upon infection and formed by replacing constitutive...

chymotrypsin-like activity of both the constitutive proteasome (PSMB5) and immunoproteasome (LMP7). It is being investigated for the treatment of hematologic malignancies...

its ability to trigger oxidative stress and elicit the expression of immunoproteasome subunits. Additionally, it has been observed to stimulate the production...

complex becomes the so-called immunoproteasome. An essential function of the modified proteasome complex, the immunoproteasome, is the processing of numerous...

proteasome assembled with these alternative subunits is known as the immunoproteasome, whose substrate specificity is altered relative to the normal proteasome...

was recently described that interferon-α-mediated stimulation of the immunoproteasome enables human TRIM5α for effective capsid-dependent inhibition of HIV-1...

through induction of antigen processing genes, including subunits of the immunoproteasome (MECL1, LMP2, LMP7), as well as TAP and ERAAP in addition possibly...

complex becomes the so-called immunoproteasome. An essential function of the modified proteasome complex, the immunoproteasome, is the processing of numerous...

biological processes. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The human PSMB7 gene has...

biological processes. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The gene PSMB5 encodes...

histocompatibility complex molecules, MHC I and MHC II, and stimulate immunoproteasome activity. All interferons drastically increase the presentation of...

biological processes. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The human gene contains...

ubiquitination of certain histones, and blocking peptide degradation by the immunoproteasome, E1A is able to reduce antigen presentation on adenovirus-infected...

non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The gene PSMD7 encodes...

Fam158a. PSME1 is a subunit of the 11S regulator which is a part of the immunoproteasome responsible for cleaving MHC class I peptides. PSME2 is another subunit...

function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred...

function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred...