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Liver disease, or hepatic disease, is any of many diseases of the liver. If long-lasting it is termed chronic liver disease. Although the diseases differ...

unknown. Renal impairment does not appear to affect the pharmacokinetic profile of zafirlukast. The hepatic clearance of zafirlukast is impaired by significant...

Hepatic encephalopathy (HE) is an altered level of consciousness as a result of liver failure. Its onset may be gradual or sudden. Other symptoms may...

in the elderly, patients with renal impairment where a reduced dose is required, and those with hepatic impairment, due to the risk of cholestatic hepatitis...

drug. Patients with a history of orthostatic hypotension or severe hepatic impairment. Interactions : No interactions were recorded when administered with...

disease or GI bleeding require special precaution. Moderate to severe liver impairment or GI toxicity can occur with or without warning symptoms in people treated...

hyperplasia. Silodosin is contraindicated for people with renal impairment or severe hepatic impairment. According to European labels, silodosin has no contraindications...

Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is the impaired liver function caused by the formation of scar...

people with mild hepatic impairment. They are decreased in people that self-identified as 'black' and those with severe renal impairment. These differences...

with moderate to severe hepatic impairment (Child-Pugh score 7–15). In patients with mild, moderate, or severe hepatic impairment, the mean AUC values for...

infarction, stroke, heart failure, coagulation disorders, renal impairment, and hepatic impairment. A common (>10%) side effect is drowsiness. Infrequent (<1%)...

hepatic impairment and in patients who are concomitantly taking a CYP1A2 inhibitor. The drug is contraindicated in patients who have severe hepatic impairment...

200 mg/day total) with food. In individuals with severe renal impairment or moderate hepatic impairment, darolutamide is used at a dosage of 300 mg orally twice...

in people with severe hepatic impairment, whereas a lower maximum dose is recommended in people with moderate hepatic impairment. Concomitant use of daridorexant...

domperidone are increased by about 2.9- and 1.5-fold in moderate hepatic impairment, respectively. Domperidone is eliminated 31% in urine and 66% in feces...

of metoprolol can vary widely among patients, often as a result of hepatic impairment or CYP2D6 polymorphism. Metoprolol was first made in 1969, patented...

orally administered azelastine is not affected by age, gender, or hepatic impairment. Azelastine is oxidatively metabolized by the cytochrome P450 family...

is increased in the elderly (to 12 hours), in hepatic impairment (to 14 hours), and in renal impairment (to 20 hours). Cetirizine contains L- and D-stereoisomers...

syndrome (unless a permanent pacemaker is in place) Patients with severe hepatic impairment (Child-Pugh class B) Patients who are hypersensitive to any component...

incidence of malignancy associated with benign adenomas; however, the size of hepatic adenoma is considered to correspond to risk of malignancy and so larger...