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There is a page named "Gene dosage" on Wikipedia
- Gene dosage is the number of copies of a particular gene present in a genome. Gene dosage is related to the amount of gene product (proteins or functional...6 KB (783 words) - 02:21, 25 May 2023
Dosage compensation is the process by which organisms equalize the expression of genes between members of different biological sexes. Across species, different...57 KB (7,670 words) - 19:48, 22 June 2024- instability, extensive gene loss, elevated levels of nucleotide substitution and regulatory network rewiring. In addition, gene dosage effects play a significant...34 KB (3,679 words) - 17:16, 24 May 2024
using gene therapy techniques to treat genetic diseases. Biological patent Epigenetics Gene-centric view of evolution Gene dosage Gene pool Gene redundancy...110 KB (12,568 words) - 07:41, 2 July 2024- automatically down-regulate gene expression, the amount of gene product (or gene dosage) will increase with each additional gene copy, until some upper limit...13 KB (1,822 words) - 15:00, 2 July 2023
8 cm (5 ft 4+1⁄8 in). The increased gene dosage of three X/Y chromosome pseudoautosomal region (PAR1) SHOX genes has been postulated as a cause of the...88 KB (9,969 words) - 05:35, 13 August 2024
Autosome (redirect from Autosomal gene)schizophrenia. Unlike single gene disorders, diseases caused by aneuploidy are the result of improper gene dosage, not nonfunctional gene product. Aneuploidy (abnormal...11 KB (1,089 words) - 01:15, 18 August 2024
Laminopathy (section Gene dosage effects)the disease is associated with a duplication of the lamin B gene LMNB1. The exact dosage of lamin B in cells appears to be crucial for nuclear integrity...32 KB (3,382 words) - 06:42, 20 May 2024
Pseudoautosomal region (section Genes)in humans, but all pseudoautosomal genes escape X-inactivation and are therefore candidates for having gene dosage effects in sex chromosome aneuploidy...10 KB (868 words) - 22:26, 2 December 2023
fatal, but there is "X-inactivation", where the effect of the additional gene dosage due to the presence of extra X chromosomes is greatly reduced. Those...12 KB (1,169 words) - 17:50, 1 August 2024
Peripheral myelin protein 22 (redirect from PMP22 (gene))serve as growth-arrest-specific (gas-3) function. Improper gene dosage of the PMP22 gene can cause aberrant protein synthesis and function of myelin...12 KB (1,472 words) - 20:31, 4 August 2024
Simeone, A (1997). "Genetic control of brain morphogenesis through Otx gene dosage requirement". Development. 124 (18): 3639–50. doi:10.1242/dev.124.18...35 KB (3,788 words) - 15:42, 24 August 2024
Copy number variation (redirect from Gene copy number)AMY1 gene is an excellent example of how gene dosage affects the survival of an organism in a given environment. The multiple copies of the AMY1 gene give...46 KB (5,325 words) - 14:06, 24 June 2024
having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which...49 KB (5,683 words) - 22:30, 5 May 2024
Non-Mendelian inheritance (section Gene conversion)X-inactivation. All female mammals have two X chromosomes. To prevent lethal gene dosage problems, one of these chromosomes is inactivated following fertilization...22 KB (2,627 words) - 12:41, 24 August 2024
stigmata, such as cubitus valgus and shortened fingers, are related to SHOX gene dosage effects. A number of the external manifestations of Turner syndrome are...77 KB (9,067 words) - 19:56, 23 August 2024
alteration in the gene dosage, which is caused by the loss of a functional allele, is also called allelic insufficiency. About 3,000 human genes cannot tolerate...11 KB (1,181 words) - 01:44, 9 February 2024
B, Pareyson D, Sghirlanzoni A, Taroni F, Steck AJ (December 1997). "Gene dosage effects in hereditary peripheral neuropathy. Expression of peripheral...82 KB (9,467 words) - 08:28, 15 August 2024
Ki-67 (protein) (redirect from MKI67 (gene))(November 2000). "Comparative methodological analysis of erbB-2/HER-2 gene dosage, chromosomal copy number and protein overexpression in breast carcinoma...10 KB (1,365 words) - 02:06, 17 June 2024- achieves two purposes. First, the eliminated copy restores the normal gene dosage in the diploid organism. Second, the changes in chromosomal genetic structure...8 KB (1,006 words) - 08:48, 20 April 2024
- have to take this for the rest of your life," often in ever-increasing dosages. Why? Because the underlying causes are not being addressed. When I lecture
- report of cerebral folate deficiency caused by a novel mutation of FOLR1 gene in a Chinese patient (2020) by Ciliu Zhang et al. 3444971First case report
- may alter gene dosage. Deletion can be extremely harmful to an organism, depending on the size and location. Some phenotypes require two genes to be present