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There is a page named "Farnesyltransferase" on Wikipedia
- Farnesyltransferase (EC 2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid...8 KB (840 words) - 03:59, 5 October 2023
- The farnesyltransferase inhibitors (FTIs) are a class of experimental cancer drugs that target protein farnesyltransferase with the downstream effect of...12 KB (1,079 words) - 17:42, 26 May 2021
- methylation. Carboxyl methylation only occurs on prenylated proteins. Farnesyltransferase and geranylgeranyltransferase I are very similar proteins. They consist...15 KB (1,810 words) - 16:46, 26 June 2024
- Farnesyl-diphosphate farnesyltransferase 1 is a protein that in humans is encoded by the FDFT1 gene. This gene encodes a membrane-associated enzyme located...1 KB (190 words) - 21:31, 3 May 2024
- 1126/science.1153018. PMC 2747771. PMID 18276850. Farnesyl-Diphosphate+Farnesyltransferase at the U.S. National Library of Medicine Medical Subject Headings...26 KB (3,078 words) - 23:35, 10 March 2024
- triggers three sequential enzymatic modifications. First, protein farnesyltransferase catalyzes the addition of a farnesyl moiety to the cysteine. Second...59 KB (6,094 words) - 01:57, 25 August 2024
- Presqualene diphosphate synthase (redirect from (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming))systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming). This enzyme catalyses the following...1 KB (118 words) - 15:31, 26 August 2023
- Tipifarnib (category Farnesyltransferase inhibitors)name Zarnestra) is a farnesyltransferase inhibitor. Farnesyltransferase inhibitors block the activity of the farnesyltransferase enzyme by inhibiting...9 KB (673 words) - 20:57, 1 December 2023
- Lonafarnib (category Farnesyltransferase inhibitors)midazolam and certain cholesterol-lowering medications. Lonafarnib, a farnesyltransferase inhibitor, is an oral medication that helps prevent the buildup of...16 KB (1,147 words) - 03:13, 24 August 2024
- affinity modulator Sickle cell disease 2019 Lonafarnib (Zokinvy) Farnesyltransferase inhibitor Hutchinson-Gilford progeria syndrome 2020 2022 Dupilumab...11 KB (842 words) - 13:15, 12 February 2024
- manipulate the regulation of the above-mentioned localization of Ras. Farnesyltransferase inhibitors have been developed to stop the farnesylation of Ras and...34 KB (4,040 words) - 14:34, 19 July 2024
- Protein farnesyltransferase subunit beta is an enzyme that in humans is encoded by the FNTB gene. GRCm38: Ensembl release 89: ENSMUSG00000033373 – Ensembl...7 KB (868 words) - 15:57, 15 January 2024
- an Ala, Met, Ser or Gln the protein will be farnesylated via the farnesyltransferase enzyme and if the X is a Leu then the protein will be geranylgeranylated...20 KB (2,232 words) - 07:44, 22 June 2024
- are used infrequently in English. Sebti; Hamilton, eds. (2001). Farnesyltransferase inhibitors in cancer therapy. p. 126. ISBN 9780896036291. Retrieved...36 KB (4,889 words) - 20:22, 23 April 2024
- treatment he devised for children affected by Progeria. He discussed how farnesyltransferase inhibitors (FTIs) affects H-Ras. After his presentation, members...12 KB (1,406 words) - 23:36, 23 April 2023
- as drug R115777) inhibits the activation of RAS. This drug is a Farnesyltransferase inhibitor which inhibits the Ras kinase in a post translational modification...30 KB (3,257 words) - 07:19, 4 August 2024
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is an enzyme that in humans is encoded by the FNTA gene. Prenyltransferases...8 KB (1,005 words) - 11:27, 13 January 2024
- 4,4'-Diapophytoene synthase (redirect from Farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase (4,4'-diapophytoene forming))enzyme with systematic name farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase (4,4'-diapophytoene forming). This enzyme catalyses the following...3 KB (270 words) - 12:43, 26 August 2023
- onto the C-terminal consensus sequence CAAL (somewhat similar to farnesyltransferase reactions), where C=cysteine, A=any aliphatic amino acid, and L=leucine...2 KB (253 words) - 19:47, 7 April 2020
- prompted intense pharmaceutical industry pursuit of inhibitors of the farnesyltransferase enzyme that catalyzes this lipid modification on RAS and other proteins...9 KB (745 words) - 10:16, 7 April 2024
- transferase. farnesyltransferase (countable and uncountable, plural farnesyltransferases) English Wikipedia has an article on: farnesyltransferase Wikipedia
- that carry out prenylation in the cell. Farnesyltransferase and geranylgeranyltransferase I Farnesyltransferase and Geranylgeranyltransferase I are very