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subunit (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent calcium channel....

clinical manifestation of a range of disorders associated with mutations in CACNA1C, the gene encoding the calcium channel Cav1.2 α subunit. The most striking...

CACNA1C-related disorders are a group of rare diseases caused by variants in the CACNA1C gene, which encodes a subunit of the L-type voltage-dependent...

shown the possibility that CACNA1C is associated with bipolar disorder and subsequently also with schizophrenia. Also, a CACNA1C risk allele has been associated...

associated with bipolar disorder, including variants within the genes CACNA1C, ODZ4, and NCAN. The largest and most recent genome-wide association study...

and altered perceptual experiences. The rs1006737 polymorphism of the CACNA1C gene is also believed to have a part in schizotypal symptoms. It may lead...

α subunit gene Phase / role Na+ INa NaV1.5 SCN5A 0 Ca2+ ICa(L) CaV1.2 CACNA1C 0-2 K+ Ito1 KV4.2/4.3 KCND2/KCND3 1, notch K+ IKs KV7.1 KCNQ1 2,3 K+ IKr...

MD/PhD in 2011. Her doctoral thesis was entitled, "The calcium channel CACNA1C gene: multiple proteins, diverse functions." She spent a year in internal...

cheetahs. •Regulation of muscle contraction (Five genes: ADORA1, ADRA1B, CACNA1C, RGS2, SCN5A). •Physiological stress response (Two genes: ADORA1, TAOK2)...

is caused by variants in the calcium channel Cav1.2 encoded by the gene CACNA1c. The following is a list of genes associated with Long QT syndrome: Although...

Some genes encode ion channels that carry calcium or potassium ions (CACNA1C, CACNB2, KCND3, KCNE3, KCNJ8, KCNT1), while others generate proteins that...

is stimulated to increase activation of the channels. CACNA1C, CACNA1D, CACNA1S, CACNA1F CACNA1C CACNA1D CACNA1S CACNA1F Felizola SJ, Maekawa T, Nakamura...

KCNJ2 have been identified with LQT7. Mutations in calcium channel gene CACNA1C have been identified with LQT8. The sodium ion channel genes SCN1A, SCN1B...

involved in calcium channel signaling with neurons. One of these genes, CACNA1C, has been found to influence cognition. It has been associated with autism...

potassium current - KCNE5, DPP10, L-type voltage gated calcium current - CACNA1C, CACNB2B, CACNA2D1, sodium current - SCN5A, SCN10A. Early repolarization...

CCAT is generated upon activation of a cryptic promoter in exon 46 of CACNA1C, the gene that encodes the voltage-gated calcium channel Cav1.2. Gomez-Ospina...

participants] Molecularly defined Timothy syndrome Monogenic disorder: CACNA1C 12  80% [in a single study composed by 17 participants] Clinically defined...

R.; Girardi, P.; Collier, D.; Frangou, S. (2011). "The impact of the CACNA1C gene polymorphism on frontolimbic function in bipolar disorder". Mol Psychiatry...

One particular SNP located on CACNA1C that confers risk for bipolar disorder is also associated with elevated CACNA1C mRNA expression in the prefrontal...

Bhatia T, Deshpande SN (2023). "Effect of rs1108580 of DBH and rs1006737 of CACNA1C on Cognition and Tardive Dyskinesia in a North Indian Schizophrenia Cohort"...