Search results

component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together with C1r and...

CRP activates the classical complement pathway via C1q binding. CRP thus forms immune complexes in the same way as IgG antibodies. This so-called acute...

is composed of the subcomponents C1q, C1r and C1s. The C1 complex is ~790 kDa and is composed of 1 molecule of C1q, 2 molecules of C1r and 2 molecules...

C1q is part of the inactive C1 complex which consists of six molecules of C1q, two molecules of C1r, and two molecules of C1s. The binding of C1q with...

complement pathway. Furthermore, pentraxins can directly bind to C1q from the C1 complex. SP-A opsonizes a number of bacterial and viral pathogens for clearance...

inflammation, abdominal pain or positive C1q antibodies to immune complexes. It is this last category, anti-C1q antibodies, that all HUV patients test positive...

complement cascade system binds C1Q complex attached to the virus surface protein via the antibodies, which in turn bind C1q receptor found on cells, bringing...

the C1-complex. The C1-complex is composed of 1 molecule of C1q, 2 molecules of C1r and 2 molecules of C1s, or C1qr2s2. This occurs when C1q binds to...

the complement, which leads to the formation of the membrane attack complex. C1q is also involved in other immunological processes such as enhancement...

TNFα, IL-1β]. PTX3 binds with high affinity to the complement component C1q, the extracellular matrix component TNFα induced protein 6 (TNFAIP6; also...

peptide-loading complex (PLC), calreticulin (along with ERp57) takes over the job of chaperoning the MHC class I protein while the tapasin links the complex to the...

protein binding metal ion binding virion binding complement component C1q complex binding carbohydrate binding identical protein binding low-density lipoprotein...

trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release...

mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation". Experimental Cell...

immune complex is formed. IgG or IgM within the immune complexes may furthermore recruit the classical pathway of the complement cascade and bind C1q which...

PMID 10383431. Tas SW, Klickstein LB, Barbashov SF, Nicholson-Weller A (Nov 1999). "C1q and C4b bind simultaneously to CR1 and additively support erythrocyte adhesion"...

β4 β5 Early stage (divided by pathway) Classical complement pathway C1Q complex - C1R / C1S C4 - C4a C2 Mannan-binding lectin pathway MASP1 / MASP2 Mannan-binding...

subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated...

in humans is encoded by the C1QBP gene. The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the...

C3b. Furthermore, host cells express p33 (globular C1q receptor) on the surface, which binds C1q, and prevents it from initiating complement activation...