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There is a page named "Beclin 1" on Wikipedia
phosphorylates and activates Beclin-1 (mammalian homologue of Atg6), which is also part of a protein complex. The autophagy-inducible Beclin-1 complex contains the...77 KB (9,112 words) - 16:54, 19 July 2024
MTOR (redirect from FK506 binding protein 12-rapamycin associated protein 1)lysosomes. TRIM16 gathers ULK1 and principal components (Beclin 1 and ATG16L1) of other complexes (Beclin 1-VPS34-ATG14 and ATG16L1-ATG5-ATG12) initiating autophagy...119 KB (12,654 words) - 00:05, 31 July 2024- the scaffold protein FIP200. Class III PI3K complex, containing hVps34, Beclin-1, p150 and Atg14-like protein or ultraviolet irradiation resistance-associated...55 KB (6,757 words) - 17:12, 15 July 2024
elucidated. Models have proposed that the active ULK1 directly phosphorylates Beclin-1 at Ser 14 and activates the pro-autophagy class III phosphoinositide 3-kinase...17 KB (1,930 words) - 14:55, 11 August 2024
Rubicon (run domain Beclin-1-interacting and cysteine-rich domain-containing protein) is a protein that in humans is encoded by the RUBCN gene. Rubicon...14 KB (1,522 words) - 18:31, 16 August 2024
(galectin-3) in the assembly of the ULK1-Beclin 1-ATG16L1 initiator complex on TRIM16 during endomembrane damage. Galectin-1 has been shown to enhance HIV infection...34 KB (3,864 words) - 01:49, 22 June 2024- identification of novel autophagy regulators, such as the components in Beclin 1-hVPS34 complex (class 3 PI3K), Atg14L, Rubicon, and NRBF2, which play crucial...22 KB (2,346 words) - 18:49, 2 August 2024
- was increased, DNA repair protein ERCC1 was decreased, autophagy protein beclin-1 was increased and, in the stem cell region at the base of crypts, there...23 KB (2,530 words) - 05:58, 17 June 2024
- infections. Neuronal expression of the mammalian autophagy promoting protein Beclin 1 protects mice against lethal Sindbis virus encephalitis " John P. Greer...5 KB (733 words) - 04:10, 24 December 2023
(2014). "Expression and clinical significance of the autophagy proteins BECLIN 1 and LC3 in ovarian cancer". Biomed Res Int. 2014: 462658. doi:10.1155/2014/462658...9 KB (1,150 words) - 01:11, 5 October 2022- pathway. The importance of mitophagy was demonstrated by the deletion of Beclin 1 and LC3b autophagy-associated genes in bone marrow-derived macrophages...33 KB (4,128 words) - 02:28, 29 June 2024
- phosphatidylserine (PS) from the ER. EMC6 interacts with the small GTPase RAB5A and Beclin-1, regulators of autophagosome formation. This observation suggests that...25 KB (3,054 words) - 06:42, 11 March 2024
HMGB1 (redirect from High-mobility group box 1)promotes cell survival by sustaining autophagy through interactions with beclin-1. It is largely considered as an antiapoptotic protein. HMGB1 can interact...26 KB (3,169 words) - 07:01, 25 July 2024- infections, showing how the herpes simplex virus type-1 expressed a protein that blocked Beclin 1 activity. She was also able to show a link between autophagy...9 KB (847 words) - 10:30, 7 April 2024
complex regulates mammalian autophagy". The Journal of Cell Biology. 191 (1): 155–168. doi:10.1083/jcb.201002100. PMC 2953445. PMID 20921139. "Autophagosome"...14 KB (1,490 words) - 22:00, 15 June 2024- predicting outcomes of colon liver metastases and that value's association with Beclin-1 expression". BioScience Trends. 11 (2): 221–228. doi:10.5582/bst.2016.01205...9 KB (703 words) - 12:31, 11 August 2024
(1): 143–53. doi:10.1016/j.jmb.2009.06.079. PMC 2739586. PMID 19580816. Chang NC, Nguyen M, Germain M, Shore GC (February 2010). "Antagonism of Beclin...4 KB (640 words) - 19:04, 10 September 2023
autophagy protein involved in ALS pathogenesis". Molecular Neurodegeneration. 14 (1): 14. doi:10.1186/s13024-019-0313-9. PMC 6437924. PMID 30917850. Ng D, Hu...5 KB (610 words) - 07:40, 22 May 2024
"A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis". PLOS ONE. 6 (3): e17086. Bibcode:2011PLoSO...5 KB (701 words) - 01:52, 4 March 2023
- data that supports the contrary. An essential protein for autophagy is Beclin-1, which has been found to suppress tumor formation. Other tumor suppressors