Search results
Appearance
There is a page named "BACE1" on Wikipedia
- Beta-secretase 1 (redirect from BACE1)1 (BACE1), membrane-associated aspartic protease 2, memapsin-2, aspartyl protease 2, and ASP2, is an enzyme that in humans is encoded by the BACE1 gene...19 KB (2,159 words) - 03:21, 5 August 2024
- opposite strand to BACE1 and is upregulated in patients with Alzheimer's disease. BACE1-AS regulates the expression of BACE1 by increasing BACE1 mRNA stability...2 KB (235 words) - 23:06, 16 March 2024
- Biomarkers of Alzheimer's disease (section BACE1)APP-cleaving enzyme 1 gene (BACE1). Dr. Zetterberg and his team used a sensitive and specific BACE1 assay to assess CSF BACE1 activity in AD. It was found...13 KB (1,704 words) - 11:44, 4 April 2024
- antisense RNA, BACE1-AS is transcribed from the opposite strand to BACE1 and is upregulated in patients with Alzheimer's disease. BACE1-AS regulates the...68 KB (7,253 words) - 04:01, 23 June 2024
- neuroinflammation of rats with Alzheimer's disease via regulating the SP1/BACE1/NLRP3/Caspase-1 signaling pathway". Bosnian Journal of Basic Medical Sciences...32 KB (3,621 words) - 17:25, 4 May 2024
- Bolon B, Damore MA, Fitzpatrick D, Liu H, Zhang J, et al. (October 2003). "BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression...44 KB (4,830 words) - 18:56, 11 August 2024
- effectively inhibited BACE1 enzymatic function, experienced problems transferring adequate, efficient levels of the antibody within the brain. BACE1 is the enzyme...20 KB (2,229 words) - 07:06, 1 December 2023
- expression of BACE1 gene. However, BACE1 expression can be activated by phosphorylation of eIF2a, which reverses the inhibitory effect exerted by BACE1 5′ UTR...36 KB (4,105 words) - 14:32, 21 December 2023
- variant of Alzheimer's amyloid precursor protein. BACE2 is a close homolog of BACE1. Cerebral deposition of amyloid beta peptide is an early and critical feature...12 KB (1,586 words) - 18:28, 8 November 2023
- acidic conditions. BACE1, BACE2 Cathepsin D Cathepsin E Chymosin (or "rennin") Napsin-A Nepenthesin Pepsin Presenilin Renin BACE1; BACE2; CTSD; CTSE;...10 KB (999 words) - 06:14, 23 February 2023
- treated with H2O2, one particular gene was examined, BACE1. The methylation level of the BACE1 CpG island was reduced (an epigenetic alteration) and...161 KB (18,344 words) - 08:31, 28 July 2024
- treated with H2O2, one particular gene was examined, BACE1. The methylation level of the BACE1 CpG island was reduced (an epigenetic alteration) and...129 KB (15,900 words) - 06:12, 13 August 2024
- Especially, the ratio of CSF neurogranin trunc P75 and the beta-secretase BACE1 is suggested as a potential marker for cognitive deterioration in the progress...7 KB (806 words) - 17:38, 11 June 2024
- Ghoshal N (Oct 2010). "Rationalizing fragment based drug discovery for BACE1: insights from FB-QSAR, FB-QSSR, multi objective (MO-QSPR) and MIF studies"...43 KB (4,323 words) - 15:18, 19 May 2024
- (January 2019). "Temporal Effects of Neuron-specific beta-secretase 1 (BACE1) Knock-in on the Mouse Brain Metabolome: Implications for Alzheimer's Disease"...9 KB (825 words) - 18:14, 5 December 2023
- have shown that specifically targeting Amyloid beta-producing genes (e.g. BACE1 and APP) by RNAi can significantly reduced the amount of Aβ peptide which...141 KB (15,474 words) - 08:09, 11 August 2024
- brain inflammation. Furthermore, nucleic acids corresponding to APP, Aβ42, BACE1, and tau protein biomarkers were found to be associated with different neurodegenerative...67 KB (7,064 words) - 08:00, 19 July 2024
- "Molecular docking studies of phlorotannins from Eisenia bicyclis with BACE1 inhibitory activity". Bioorganic & Medicinal Chemistry Letters. 20 (11):...7 KB (716 words) - 07:40, 11 December 2023
- Q14032 1396 BABAM1 HGNC:25008 Q9NWV8 1397 BABAM2 HGNC:1106 Q9NXR7 1398 BACE1 HGNC:933 P56817 1399 BACE2 HGNC:934 Q9Y5Z0 1400 BACH1 HGNC:935 O14867 1401...277 KB (17 words) - 23:17, 27 April 2024
- treatment of Alzheimer's disease. It is an inhibitor of beta-secretase 1 (BACE1), which, after initial promise proved disappointing. In April 2012 phase...8 KB (575 words) - 18:14, 5 December 2023
- Irish researchers have focused on the enzyme beta-secretase (BACE1) activity in the brain. (BACE1 is one of two enzymes involved in the pathological processing