Urine cytology: Difference between revisions
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'''Urine cytology''' is a test that looks for abnormal cells in [[urine]] |
'''Urine cytology''' is a test that looks for abnormal cells in [[urine]] under a microscope. The test commonly checks for infection, inflammatory disease of the [[urinary tract]], [[cancer]], or [[precancer]]ous conditions. If a cancerous condition is detected, other tests and procedures are usually recommended to diagnose cancers, including [[bladder cancer]], [[ureteral cancer]] and [[cancer of the urethra]]. It is especially recommended when blood in the urine ([[hematuria]]) has been detected. |
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Urine typically contains [[epithelial cell]]s shed from the urinary tract, and urine cytology evaluates this urinary sediment for the presence of cancerous cells<ref>{{Cite web |url=https://www.mayoclinic.org/tests-procedures/urine-cytology/about/pac-20385279 |title=Urine cytology - Mayo Clinic|website=www.mayoclinic.org|access-date=2019-02-27}}</ref> from the lining of the urinary tract, and it is a convenient noninvasive technique for follow-up analysis of patients treated for urinary tract cancers. |
Urine typically contains [[epithelial cell]]s shed from the urinary tract, and urine cytology evaluates this urinary sediment for the presence of cancerous cells<ref>{{Cite web |url=https://www.mayoclinic.org/tests-procedures/urine-cytology/about/pac-20385279 |title=Urine cytology - Mayo Clinic|website=www.mayoclinic.org|access-date=2019-02-27}}</ref> from the lining of the urinary tract, and it is a convenient noninvasive technique for follow-up analysis of patients treated for urinary tract cancers. |
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For this process, urine must be collected in a reliable fashion, and if urine samples are inadequate, the urinary tract can be assessed via [[instrumentation]]. In urine cytology, collected urine is examined microscopically. One limitation, however, is the inability to definitively identify [[Grading (tumors)|low-grade]] cancer cells and urine cytology is used mostly to identify high-grade [[tumor]]s.<ref>{{Cite journal |last=Auger |first=Manon |last2=Kassouf |first2=Wassim |last3=Aprikian |first3=Armen|last4=Case|first4=Bruce|last5=Vollmer|first5=Robin T. |last6=Brimo |first6=Fadi|date=2009-11-01|title=Accuracy of Urine Cytology and the Significance of an Atypical Category |url=https://academic.oup.com/ajcp/article/132/5/785/1766588 |journal=American Journal of Clinical Pathology|language=en|volume=132|issue=5|pages=785–793 |doi=10.1309/AJCPPRZLG9KT9AXL |pmid=19846822|issn=0002-9173}}</ref> |
For this process, urine must be collected in a reliable fashion, and if urine samples are inadequate, the urinary tract can be assessed via [[instrumentation]], such as a [[catheter]]. In urine cytology, collected urine is examined microscopically. |
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One limitation, however, is the inability to definitively identify [[Grading (tumors)|low-grade]] cancer cells and urine cytology is used mostly to identify high-grade [[tumor]]s.<ref>{{Cite journal |last=Auger |first=Manon |last2=Kassouf |first2=Wassim |last3=Aprikian |first3=Armen|last4=Case|first4=Bruce|last5=Vollmer|first5=Robin T. |last6=Brimo |first6=Fadi|date=2009-11-01|title=Accuracy of Urine Cytology and the Significance of an Atypical Category |url=https://academic.oup.com/ajcp/article/132/5/785/1766588 |journal=American Journal of Clinical Pathology|language=en|volume=132|issue=5|pages=785–793 |doi=10.1309/AJCPPRZLG9KT9AXL |pmid=19846822|issn=0002-9173}}</ref> |
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If the test detects atypical or cancerous cells, further tests may be recommended, such as [[cystoscopy]] and a [[CT scan]]. |
If the test detects atypical or cancerous cells, further tests may be recommended, such as [[cystoscopy]] and a [[CT scan]]. |
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Revision as of 23:21, 27 July 2019
Urine cytology is a test that looks for abnormal cells in urine under a microscope. The test commonly checks for infection, inflammatory disease of the urinary tract, cancer, or precancerous conditions. If a cancerous condition is detected, other tests and procedures are usually recommended to diagnose cancers, including bladder cancer, ureteral cancer and cancer of the urethra. It is especially recommended when blood in the urine (hematuria) has been detected.
Urine typically contains epithelial cells shed from the urinary tract, and urine cytology evaluates this urinary sediment for the presence of cancerous cells[1] from the lining of the urinary tract, and it is a convenient noninvasive technique for follow-up analysis of patients treated for urinary tract cancers.
For this process, urine must be collected in a reliable fashion, and if urine samples are inadequate, the urinary tract can be assessed via instrumentation, such as a catheter. In urine cytology, collected urine is examined microscopically.
One limitation, however, is the inability to definitively identify low-grade cancer cells and urine cytology is used mostly to identify high-grade tumors.[2]
If the test detects atypical or cancerous cells, further tests may be recommended, such as cystoscopy and a CT scan.
References
- ^ "Urine cytology - Mayo Clinic". www.mayoclinic.org. Retrieved 2019-02-27.
- ^ Auger, Manon; Kassouf, Wassim; Aprikian, Armen; Case, Bruce; Vollmer, Robin T.; Brimo, Fadi (2009-11-01). "Accuracy of Urine Cytology and the Significance of an Atypical Category". American Journal of Clinical Pathology. 132 (5): 785–793. doi:10.1309/AJCPPRZLG9KT9AXL. ISSN 0002-9173. PMID 19846822.
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