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An inotrope or inotropic is a drug or any substance that alters the force or energy of muscular contractions. Negatively inotropic agents weaken the force...

increases the strength of the heart's contractions, leading to a positive inotropic effect. Generally it has little effect on a person's heart rate. Dobutamine...

positive inotropic and chronotropic effects on the heart. β2 adrenoceptor stimulation in arteriolar smooth muscle induces vasodilation. Its inotropic and chronotropic...

without a rise in intracellular calcium. Levosimendan exerts its positive inotropic effect by increasing calcium sensitivity of myocytes by binding to cardiac...

stimulation). Agents that are dromotropic are often (but not always) inotropic and chronotropic. For instance, parasympathetic stimulation is usually...

Reducing the force of contraction of the myocardium is known as the negative inotropic effect of calcium channel blockers. Slowing down the conduction of electrical...

reduced ventricular function may not be able to counteract the negative inotropic and chronotropic effects of diltiazem, the result being an even higher...

modulation of olfactory driven behaviors. Both positive and negative inotropic effects on heart muscle Secretion from salivary gland Increase salivary...

calcium back in the sarcoplasmic reticulum., Istaroxime is a positive inotropic agent that mediates its action through inhibition of sodium/potassium...

receptor agonist derived from tetrahydroisoquinoline. It has a positive inotropic effect, suggesting potential use in treatment of chronic heart failure...

puncture tries, long duration of cannulation, administration of vasopressor/inotropic agents, and the usage of catheters with side holes. Acoustic angiography...

increased uptake leads to increased myocardial contractility (positive inotropic effect), but the myocardial relaxation, or lusitropy, decreases. This...

used digoxin and digitoxin, deal with the latter, due to their positive inotropic activity. On the other hand, cardiac arrhythmia are changes in heart rate...

and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in the management of heart...

introduction of digitalis, though it turns out that digitalis has an inotropic effect rather than a chronotropic effect. Beta blockers such as metoprolol...

by epinephrine and norepinephrine induces a positive chronotropic and inotropic effect on the heart and increases cardiac conduction velocity and automaticity...

with packed red blood cells Cardiogenic shock Cardiac output Positive inotropic agents / Chronotropes Distributive shock Sepsis (Septic shock) Vascular...

response to beta-adrenergic stimulation and important in increasing the inotropic response. Phosphorylation of cTnI changes the conformation of the protein...

the type of receptor. For instance, neurotransmitters that bind with an inotropic receptor can alter the excitability of a target cell. Other types of receptors...

are considered to have a positive inotropic effect. The ancient herbal remedy digitalis appears to have both inotropic and chronotropic properties that...