User:Bujesse/sandbox

Guojun Bu is the Chair of Neuroscience at Mayo Clinic Jacksonville (MCJ).^[1] His research is centered on understanding why a specific allele of the apolipoprotein E gene, APOE ɛ4, represents a strong risk factor for Alzheimer's disease (AD). Dr. Bu's Neurobiology of Alzheimer's Disease Laboratory is focused on identifying risk factors for developing Alzheimer's disease to develop new ways to diagnose the disease earlier and develop new treatments.^[2]

Dr. Bu has published over 350 scientific papers including the top three most cited papers in the field of Alzheimer's disease research TODO.^[3]

Dr. Bu is also an Editor-in-Chief of Molecular Neurodegeneration which is an open access, peer-reviewed journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.^[4]

Authored books?

TODO: Need years, academic accolades, etc.

• Post Doctoral Research: Washington University

• PhD - Biochemistry: Virginia Polytechnic Institute & State University

• BS - Biology: Beijing Normal University

Bu discovered (with others) // TODO

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• Associate Director, Center for Regenerative Medicine, Mayo Clinic, Florida, 2017-present
• Recipient, Award for Medical Research in Alzheimer's Disease, MetLife Foundation, 2016
• Recipient, Mayo Clinic Investigator of the Year Award, 2015
• Recipient, Zenith Fellows Award, Alzheimer's Association,

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• 1983: Helped localize the Huntington’s disease gene via genetic linkage (with James F. Gusella and Anne Young).
• 1984-1988: Was among first to clone the amyloid precursor protein (APP) gene and map it to chromosome 21, for which he produced the first map.
• 1993: Carried out chromosome 21 physical mapping leading to first familial ALS gene-SOD1.

• Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, Donaldson D, Goto J, O'Regan JP, Deng HX, et al. "Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis."
• Gusella JF, Wexler NS, Conneally PM, Naylor SL, Anderson MA, Tanzi RE, Watkins PC, Ottina K, Wallace MR, Sakaguchi AY, Young AB, Shoulson I, Bonilla E, Martin JB. "A polymorphic DNA marker genetically linked to Huntington's Disease." Nature 1983; 306: 234-238.
• Tanzi, RE, Gusella JF, Watkins PC, Bruns GAP, St. George-Hyslop PH, Van Keuren ML, Patterson D, Pagan S, Kurnit DM, Neve RL. "The amyloid beta protein gene: cDNA cloning, mRNA distribution, and genetic linkage near the Alzheimer locus." Science 1987; 235: 880-884.
• Tanzi RE, McClatchey AI, Lamperti ED, V-Komaroff L, Gusella JF, Neve R. Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature, 1988; 331: 528-530.