Histoid leprosy
| Histoid leprosy | |
|---|---|
| Specialty | Dermatology |
Histoid leprosy is a skin condition, a rare form of multibacillary leprosy.[1]: 346 It can occur in those with relapsing leprosy after undergoing antibiotic therapy with dapsone, or less frequently in the first infection (termed de novo).[2]
Leprosy can appear in two forms, tuberculoid leprosy and lepromatous leprosy, and histoid leprosy is a variant of lepromatous leprosy. It appears as "cutaneous and/or subcutaneous nodules and papules, which are painless, succulent, discrete, smooth, globular, skin-colored to yellowish-brown, with apparently normal skin surrounding it."[3] In India, histoid leprosy is estimated to compose 2.79%-3.6% of all leprosy cases. The male to female ratio in most parts of the world is 2:1. It is treated with antimycobacterial chemotherapy and multibacillary multidrug therapy.[3]
See also
References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ Pandey, Pooja; Suresh, Mavinrkainahalli Srinivasa Murthy; Dey, Vivek Kumar (2015). "De Novo Histoid Leprosy". Indian Journal of Dermatology. 60 (5): 525. doi:10.4103/0019-5154.159666. ISSN 1998-3611. PMC 4601467. PMID 26538746.
- ^ a b Gupta, Sunil Kumar (2015-06-20). "Histoid leprosy: review of the literature". International Journal of Dermatology. 54 (11): 1283–1288. doi:10.1111/ijd.12799. ISSN 0011-9059.