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Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the...

Desmoglein-1 is a protein that in humans is encoded by the DSG1 gene. Desmoglein-1 is expressed everywhere in the skin epidermis, but mainly it is expressed...

autoimmune disease caused by antibodies directed against both desmoglein 1 and desmoglein 3 present in desmosomes. Loss of desmosomes results in loss of...

which auto-antibodies target desmogleins. PV is caused by circulating autoantibodies (IgG) that target Dsg3 (Desmoglein 3) and sometimes Dsg1. PV is manifested...

The desmogleins are a family of desmosomal cadherins consisting of proteins DSG1, DSG2, DSG3, and DSG4. They play a role in the formation of desmosomes...

This is in contrast to pemphigus vulgaris, which has antibodies against desmoglein-3 primarily. Patients with pemphigus erythematosus will have positive ANA...

pemphix, meaning "blister". In pemphigus, autoantibodies form against desmoglein, which forms the "glue" that attaches adjacent epidermal cells via attachment...

Exfoliatins are glutamate-specific serine proteases highly specific to desmoglein I, a cadherin (adhesion protein) in the desmosomes of the stratum granulosum...

IgG autoantibodies that are characteristically raised against desmoglein 1 and desmoglein 3 (which are cell-cell adhesion molecules found in desmosomes)...

A Clinician's Guide to Pemphigus Vulgaris. Springer, Cham. pp. 3–10. doi:10.1007/978-3-319-67759-0_1. ISBN 9783319677583. Bolognia, Jean L.; et al. (2007)...

John P. (2017-03-16). "Alopecia areata". Nature Reviews Disease Primers. 3 (1). Springer Science and Business Media LLC: 17011. doi:10.1038/nrdp.2017...

neurofilament and MAP-2-expressing neuronal cells in the spinal cord and brain, desmoglein-3-, cytokerain14- and cytokeratin 15-expressing epidermal cells in the...

constitute a novel marker of primary biliary cirrhosis". Gastroenterology. 110 (3): 840–7. doi:10.1053/gast.1996.v110.pm8608894. PMID 8608894. Szostecki C,...

vulgaris IgG Desmoglein 3 130 Mucocutaneous pemphigus vulgaris IgG Desmoglein 3 Desmoglein 1 130 160 Pemphigus foliaceus IgG Desmoglein 1 160 Paraneoplastic...

Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. Desmoglein-2 is highly expressed in epithelial cells and cardiomyocytes. Desmoglein-2...

desmoglein 1. The effect of the antibodies and the immunological pathway is most likely one of three mechanisms: Steric hindrance of the desmoglein 1:...

Desmoglein-4 is a protein that in humans is encoded by the DSG4 gene. List of conditions caused by problems with junctional proteins GRCh38: Ensembl release...

immunoprecipitation, target antigens have been found to include desmoglein-3, desmoglein-1, envoplakin, periplakin, desmoplakin 1, desmoplakin 2, and bullous...

061 – centromere protein b MeSH D23.050.422.124 – desmoglein 1 MeSH D23.050.422.249 – desmoglein 3 MeSH D23.050.422.500 – heymann nephritis antigenic...

"Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface". J. Clin. Invest. 122 (10): 3781–3790. doi:10.1172/JCI64413...